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[These data indicate that there is an overexpression of CTGF in the systemic sclerosis cells, probably due to increased gene transcription, and suggest that the dysregulation of CTGF production is an important factor in fibroblast activation and the excessive deposition of collagen in systemic sclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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