sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_5 ;
    pav:version "20131211" .
  sub:_4 prov:value "The concentration of cholesterol in cell membranes, including the membrane of the Sarcoplasmic Reticulum/Golgi Apparatus system, is the signal to regulate the connection between the transcription factor, Sterol Regulatory Element Binding Protein (SREBP), and its anchor protein SREBP-Cleavage Activating Protein (SCAP). Cytoplasmic sequestration of SREBP by SCAP prevents the synthesis of LDL-R and other enzymes involved in cholesterol synthesis, especially HMG-CoA-R. The higher the concentration of cholesterol in cell membranes, the greater the inhibition of the synthesis of LDL-R." ;
    prov:wasQuotedFrom pubmed:21461336 .
  sub:_5 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:21461336 ;
    prov:wasDerivedFrom beldoc: , sub:_4 .
}