. . . . . . . . . . . . "[CREM knock-out mice exhibit significantly less anxiety behavior than wild-type mice and the alternative CREM gene product inducible cAMP early repressor (ICER) plays a pivotal role in the hypothalamo-pituitary-adrenal (HPA) axis, which is disturbed in panic disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2016-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2016-05-13T12:44:38+02:00"^^ . . . . . . . . . . . "v4.0.0.0" . "v4.0.0" .