[Other results followed: Expression of CXCR4 and TNF-alpha was upregulated in gastric cancer cell MKN45 and HGC27 after infection with H. pylori 26695 (cag PAI+ ) or Tx30a (cag PAI- ); The induction of CXCR4 expression by H. pylori was inhibited significantly by a neutralizing TNF-alpha antibody, infliximab; CXCR4 expression was upregulated in MKN45 cells after treatment with exogenous TNF-alpha or co-culture with macrophage, and was downregulated in HGC27 cells after transfection with TNF-alpha RNAi plasmid.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
Gene-disease associations inferred from text-mining the literature.
DisGeNET evidence - LITERATURE