sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_6 ;
    pav:version "20131211" .
  sub:_5 prov:value "To determine the cytotoxic effects and the type of cell death facilitated by TNF in A549 cells, we treated cells with TNF and analyzed cell death based on morphological and biochemical assays. The death rate of A549 cells increased with increasing concentration of TNF (Fig. 1b), and cell death was characterized by cytoplasmic condensation and pyknotic nuclei without apoptotic body formation (Fig. 1c). Dose-dependent release of LDH into the culture medium was also noted (Fig. 1d); this is frequently encountered after necrotic cell death due to rupture of the cell membrane....Thus, TNF triggers necrotic rather than apoptotic cell death in A549 cells." ;
    prov:wasQuotedFrom pubmed:20963496 .
  sub:_6 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:20963496 ;
    prov:wasDerivedFrom beldoc: , sub:_5 .
}