@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP1280493.RAonu6GuxO9Od8dSKjoBXRvOtq_IsYsKNFXYwOGONpvtY130_head { this: np:hasAssertion dgn-np:NP1280493.RAonu6GuxO9Od8dSKjoBXRvOtq_IsYsKNFXYwOGONpvtY130_assertion; np:hasProvenance dgn-np:NP1280493.RAonu6GuxO9Od8dSKjoBXRvOtq_IsYsKNFXYwOGONpvtY130_provenance; np:hasPublicationInfo dgn-np:NP1280493.RAonu6GuxO9Od8dSKjoBXRvOtq_IsYsKNFXYwOGONpvtY130_publicationInfo; a np:Nanopublication . dgn-np:NP1280493.RAonu6GuxO9Od8dSKjoBXRvOtq_IsYsKNFXYwOGONpvtY130_assertion a np:Assertion . dgn-np:NP1280493.RAonu6GuxO9Od8dSKjoBXRvOtq_IsYsKNFXYwOGONpvtY130_provenance a np:Provenance . dgn-np:NP1280493.RAonu6GuxO9Od8dSKjoBXRvOtq_IsYsKNFXYwOGONpvtY130_publicationInfo a np:PublicationInfo . } dgn-np:NP1280493.RAonu6GuxO9Od8dSKjoBXRvOtq_IsYsKNFXYwOGONpvtY130_assertion { miriam-gene:5010 a ncit:C16612 . lld:C0026769 a ncit:C7057 . dgn-gda:DGN904aec3702e2f9eab39e28371b8b8122 sio:SIO_000628 miriam-gene:5010, lld:C0026769; a sio:SIO_001121 . } dgn-np:NP1280493.RAonu6GuxO9Od8dSKjoBXRvOtq_IsYsKNFXYwOGONpvtY130_provenance { dgn-np:NP1280493.RAonu6GuxO9Od8dSKjoBXRvOtq_IsYsKNFXYwOGONpvtY130_assertion dcterms:description "[Here, we analyzed the impact of the different HLA-DR15 haplotype alleles on disease susceptibility in a new humanized model of MS induced in HLA-transgenic (Tg) mice by human oligodendrocyte-specific protein (OSP)/claudin-11 (hOSP), one of the bona fide potential primary target antigens in MS. We show that the hOSP-associated MS-like disease is dominated by the DRB1*15:01 allele not only as the DRA1*01:01;DRB1*15:01 isotypic heterodimer but also, unexpectedly, as a functional DQA1*01:02;DRB1*15:01 mixed isotype heterodimer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:25911099; prov:wasDerivedFrom dgn-void:befree-2016; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP1280493.RAonu6GuxO9Od8dSKjoBXRvOtq_IsYsKNFXYwOGONpvtY130_publicationInfo { this: dcterms:created "2016-05-13T12:51:26+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetv3.0rdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v4.0.0.0" . dgn-void:disgenetv3.0rdf pav:version "v4.0.0" . }