@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .
dgn-np:NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_head {
   this: np:hasAssertion dgn-np:NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_assertion ;
    np:hasProvenance dgn-np:NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_provenance ;
    np:hasPublicationInfo dgn-np:NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_publicationInfo ;
    a np:Nanopublication .
  dgn-np:NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_assertion a np:Assertion .
  dgn-np:NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_provenance a np:Provenance .
  dgn-np:NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_publicationInfo a np:PublicationInfo .
}
dgn-np:NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_assertion {
   miriam-gene:10497 a ncit:C16612 .
  lld:C0030567 a ncit:C7057 .
  dgn-gda:DGNae905d2d3fcb73f0b056fa7d2cba4da6 sio:SIO_000628 miriam-gene:10497 , lld:C0030567 ;
    a sio:SIO_001121 .
}
dgn-np:NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_provenance {
   dgn-np:NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_assertion dcterms:description "[Psychotropic drugs can meaningfully affect PD risk gene mRNA transcription, including antipsychotics (upregulate dopamine receptors D2 and D3 (DRD2, DRD3); downregulate low-density lipoprotein receptor-related protein 8 (LRP8), ubiquitin carboxyl-terminal esterase L1 (UCHL1, also known as PARK5)), haloperidol (upregulates DRD3, parkin (PRKN, also known as PARK2), DRD2; downregulates brain-derived neurotrophic factor (BDNF)), risperidone (upregulates monoamine oxidase B (MAOB), DRD2), olanzapine (upregulates transmembrane protein 163 (TMEM163), BDNF, glutathione S-transferase mu 1 (GSTM1), MAOB, DRD2, solute carrier organic anion transporter family, member 3A1 (SLCO3A1)), aripiprazole (upregulates DRD2), quetiapine, paliperidone, lurasidone, carbamazepine, and many antidepressants (upregulate BDNF), lithium and bupropion (downregulate BDNF), amitriptyline (upregulates DRD3, DRD2), imipramine (upregulates BDNF, DRD3, DRD2), desipramine (upregulates BDNF, DRD3), and fluoxetine (upregulates acid beta-glucosidase (GBA), coiled-coil domain containing 62 (CCDC62), BDNF, DRD3, UCHL1, unc-13 homolog B (UNC13B), and perhaps huntingtin interacting protein 1 related (HIP1R); downregulates microtubule-associated protein tau (MAPT), methylcrotonoyl-coenzyme A carboxylase I (MCCC1), GSTM1, 28kDa calbindin 1 (CALB1)).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en ;
    wi:evidence dgn-void:source_evidence_literature ;
    sio:SIO_000772 miriam-pubmed:22507762 ;
    prov:wasDerivedFrom dgn-void:befree-20140225 ;
    prov:wasGeneratedBy eco:ECO_0000203 .
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  dgn-void:source_evidence_literature a eco:ECO_0000212 ;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en ;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}
dgn-np:NP721908.RAobG2E1vrvK76kDul8Sk0BOsfS32Xwa0OqKypaum2avM130_publicationInfo {
   this: dcterms:created "2014-10-02T12:39:18+02:00"^^xsd:dateTime ;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/> ;
    dcterms:rightsHolder dgn-void:IBIGroup ;
    dcterms:subject sio:SIO_000983 ;
    prv:usedData dgn-void:disgenetrdf ;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269> , <http://orcid.org/0000-0002-7534-7661> , <http://orcid.org/0000-0002-9383-528X> , <http://orcid.org/0000-0003-0169-8159> , <http://orcid.org/0000-0003-1244-7654> ;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159> ;
    pav:version "v2.1.0.0" .
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}