http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#head
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://www.nanopub.org/nschema#hasAssertion
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#assertion
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://www.nanopub.org/nschema#hasProvenance
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#provenance
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://www.nanopub.org/nschema#hasPublicationInfo
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#publicationInfo
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.nanopub.org/nschema#Nanopublication
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#assertion
http://rdf.disgenet.org/resource/gda/DGN962d41bf6c592a2c0dfc258a5e92d5fa
http://semanticscience.org/resource/SIO_000628
http://identifiers.org/ncbigene/57142
http://rdf.disgenet.org/resource/gda/DGN962d41bf6c592a2c0dfc258a5e92d5fa
http://semanticscience.org/resource/SIO_000628
http://linkedlifedata.com/resource/umls/id/C0935572
http://rdf.disgenet.org/resource/gda/DGN962d41bf6c592a2c0dfc258a5e92d5fa
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://semanticscience.org/resource/SIO_001121
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#provenance
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#assertion
http://purl.org/dc/terms/description
[The following observations were made: (i) recent isolates showed an about 2-fold increase in the number of glycosylation sites of HA and NA when compared to isolates from 1968 to 1970; (ii) during passages of clinical strains in CACO-2 and MDCK cells HA and NA mutated cooperatively with strain-specific variations implying that functioning of the HA-NA complex varied from strain to strain in one influenza outbreak; (iii) there were no amino acid exchanges in the HA receptor binding site although the viruses acquired the ability to agglutinate avian erythrocytes after passage in MDCK cells, suggesting that virus adsorption is regulated by several factors; (iv) quasispecies characterized by deletion of 66 nucleotides (22 amino acids) in the stalk region of the NA gene was dominant in naso-pharyngeal washes of all patients whereas during passaging in CACO-2 cells this deleted genotype in isolates from different patients was either stably retained as prevalent quasispecies or rapidly replaced for that one containing full length NA gene; (v) the M2 protein of clinical viruses was sensitive to amantadine; (vi) the NS segment of human viruses, unlike the most of avian ones, contained an additional positive-sense open reading frame encoding a hypothetical 25kD polypeptide (negative strand protein, NSP).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#assertion
http://purl.org/ontology/wi/core#evidence
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#assertion
http://semanticscience.org/resource/SIO_000772
http://identifiers.org/pubmed/19546028
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#assertion
http://www.w3.org/ns/prov#wasDerivedFrom
http://rdf.disgenet.org/v5.0.0/void/BEFREE
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#assertion
http://www.w3.org/ns/prov#wasGeneratedBy
http://purl.obolibrary.org/obo/ECO_0000203
http://rdf.disgenet.org/v5.0.0/void/BEFREE
http://purl.org/pav/importedOn
2017-02-19
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://purl.obolibrary.org/obo/ECO_0000212
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://www.w3.org/2000/01/rdf-schema#comment
Gene-disease associations inferred from text-mining the literature.
http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature
http://www.w3.org/2000/01/rdf-schema#label
DisGeNET evidence - LITERATURE
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg#publicationInfo
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/dc/terms/created
2017-10-17T13:18:44+02:00
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/dc/terms/rights
http://opendatacommons.org/licenses/odbl/1.0/
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/dc/terms/rightsHolder
http://rdf.disgenet.org/v5.0.0/void/IBIGroup
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/dc/terms/subject
http://semanticscience.org/resource/SIO_000983
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/net/provenance/ns#usedData
http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/pav/authoredBy
http://orcid.org/0000-0001-5999-6269
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/pav/authoredBy
http://orcid.org/0000-0002-7534-7661
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/pav/authoredBy
http://orcid.org/0000-0002-9383-528X
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/pav/authoredBy
http://orcid.org/0000-0003-0169-8159
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/pav/authoredBy
http://orcid.org/0000-0003-1244-7654
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/pav/createdBy
http://orcid.org/0000-0003-0169-8159
http://rdf.disgenet.org/resource/nanopub/NP1346653.RAo_b7_nLYgnbmjyqEvrJfgz04o6QIpdI2BgbwV-pt4dg
http://purl.org/pav/version
v5.0.0.0
http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf
http://purl.org/pav/version
v5.0.0