@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP573935.RAo6MGwVNFjkAoJLSo45JIbrRevmzGIWRJ03fiNVKLlvw130_head { this: np:hasAssertion dgn-np:NP573935.RAo6MGwVNFjkAoJLSo45JIbrRevmzGIWRJ03fiNVKLlvw130_assertion; np:hasProvenance dgn-np:NP573935.RAo6MGwVNFjkAoJLSo45JIbrRevmzGIWRJ03fiNVKLlvw130_provenance; np:hasPublicationInfo dgn-np:NP573935.RAo6MGwVNFjkAoJLSo45JIbrRevmzGIWRJ03fiNVKLlvw130_publicationInfo; a np:Nanopublication . dgn-np:NP573935.RAo6MGwVNFjkAoJLSo45JIbrRevmzGIWRJ03fiNVKLlvw130_assertion a np:Assertion . dgn-np:NP573935.RAo6MGwVNFjkAoJLSo45JIbrRevmzGIWRJ03fiNVKLlvw130_provenance a np:Provenance . dgn-np:NP573935.RAo6MGwVNFjkAoJLSo45JIbrRevmzGIWRJ03fiNVKLlvw130_publicationInfo a np:PublicationInfo . } dgn-np:NP573935.RAo6MGwVNFjkAoJLSo45JIbrRevmzGIWRJ03fiNVKLlvw130_assertion { miriam-gene:1441 a ncit:C16612 . lld:C2931027 a ncit:C7057 . dgn-gda:DGNf860e86678a4cd3e0baecf82ef83e8c1 sio:SIO_000628 miriam-gene:1441, lld:C2931027; a sio:SIO_001121 . } dgn-np:NP573935.RAo6MGwVNFjkAoJLSo45JIbrRevmzGIWRJ03fiNVKLlvw130_provenance { dgn-np:NP573935.RAo6MGwVNFjkAoJLSo45JIbrRevmzGIWRJ03fiNVKLlvw130_assertion dcterms:description "[Although one of these (Y704) has previously been shown to be involved in STAT3 activation from a truncated G-CSF-R derived from a patient with severe chronic neutropenia (SCN), this tyrosine is not required for STAT3 activation by the full-length G-CSF-R. To investigate possible alternative mechanisms of STAT3 activation, we generated a series of Ba/F3 cell transfectants expressing the wild-type G-CSF-R or mutant receptors that either completely lack tyrosines or retain just one of the four cytoplasmic tyrosines of the G-CSF-R. We show that, at saturating G-CSF concentrations, STAT3 activation from the full-length G-CSF-R is efficiently mediated by the C-terminal domain in a manner independent of receptor tyrosines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:9864153; prov:wasDerivedFrom dgn-void:befree-20140225; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP573935.RAo6MGwVNFjkAoJLSo45JIbrRevmzGIWRJ03fiNVKLlvw130_publicationInfo { this: dcterms:created "2014-10-02T12:37:46+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetrdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v2.1.0.0" . dgn-void:disgenetrdf pav:version "v2.1.0" . }