sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_7 ; pav:version "20131211" . sub:_6prov:value "Figure 5. This is a figure in the review representing the cross talk between FGFR3 and IL6 signaling in multiple myeloma cell line KH11; the legend is as follows: Fig. 5. Enhanced proliferation of myeloma cells by interleu- kin- 6 cooperatingwith FGFR3-mediated signals. IL- 6 and FGF induce the distinct intracellular signaling pathways in myeloma cells carryingt(4 ;14)(p16. 3 ;q32) that ectopically express FGFR3. FGF and IL- 6 activate ERK1/ 2, PI- 3 kinase and STAT3, respectively. The serine phosphorylation of STAT3 via the FGF- induced ERK1/ 2 activation contributes to the full activation of STAT3, leadingto the expression of c-myc and bcl- 2 genes and cell proliferation 91 .FRS:FGF receptor substrate." ; prov:wasQuotedFrompubmed:17142955 . sub:_7rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:17142955 ; prov:wasDerivedFrombeldoc: , sub:_6 . }