@prefix this: <
http://www.tkuhn.ch/bel2nanopub/RAnGILXbqySlyZYoxvcK_6PelZKaxxk7aV7mz0ZkNqcus
> .
@prefix sub: <
http://www.tkuhn.ch/bel2nanopub/RAnGILXbqySlyZYoxvcK_6PelZKaxxk7aV7mz0ZkNqcus#
> .
@prefix beldoc: <
http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel
> .
@prefix rdfs: <
http://www.w3.org/2000/01/rdf-schema#
> .
@prefix rdf: <
http://www.w3.org/1999/02/22-rdf-syntax-ns#
> .
@prefix xsd: <
http://www.w3.org/2001/XMLSchema#
> .
@prefix dct: <
http://purl.org/dc/terms/
> .
@prefix dce: <
http://purl.org/dc/elements/1.1/
> .
@prefix pav: <
http://purl.org/pav/
> .
@prefix np: <
http://www.nanopub.org/nschema#
> .
@prefix belv: <
http://www.selventa.com/vocabulary/
> .
@prefix prov: <
http://www.w3.org/ns/prov#
> .
@prefix go: <
http://amigo.geneontology.org/amigo/term/GO:
> .
@prefix Protein: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
> .
@prefix hgnc: <
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=
> .
@prefix geneProductOf: <
http://purl.obolibrary.org/obo/RO_0002204
> .
@prefix hasAgent: <
http://semanticscience.org/resource/SIO_000139
> .
@prefix chebi: <
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=
> .
@prefix obo: <
http://purl.obolibrary.org/obo/
> .
@prefix occursIn: <
http://purl.obolibrary.org/obo/BFO_0000066
> .
@prefix species: <
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=
> .
@prefix pubmed: <
http://www.ncbi.nlm.nih.gov/pubmed/
> .
@prefix orcid: <
http://orcid.org/
> .
sub:Head
{
this:
np:hasAssertion
sub:assertion
;
np:hasProvenance
sub:provenance
;
np:hasPublicationInfo
sub:pubinfo
;
a
np:Nanopublication
.
}
sub:assertion
{
sub:_1
hasAgent:
sub:_2
;
a
go:0003824
.
sub:_2
geneProductOf:
hgnc:7889
;
a
Protein:
.
sub:_3
occursIn:
obo:UBERON_0004237
,
species:9606
;
rdf:object
chebi:26523
;
rdf:predicate
belv:increases
;
rdf:subject
sub:_1
;
a
rdf:Statement
.
sub:assertion
rdfs:label
"cat(p(HGNC:NOX1)) -> a(CHEBI:\"reactive oxygen species\")" .
}
sub:provenance
{
beldoc:
dce:description
"Approximately 61,000 statements." ;
dce:rights
"Copyright (c) 2011-2012, Selventa. All rights reserved." ;
dce:title
"BEL Framework Large Corpus Document" ;
pav:authoredBy
sub:_5
;
pav:version
"20131211" .
sub:_4
prov:value
"ANG II activates membrane NAD(P)H oxidases in VSMCs to produce ROS such as superoxide and hydrogen peroxide (H2O2), which are involved in the pleiotrophic effects of ANG II (63, 153, 204, 221). The mechanism by which ANG II activates NAD(P)H oxidases remains under intense investigation. In aortic smooth muscle cells, the NAD(P)H oxidase subunits Nox1 and Nox4 are mainly responsible for ROS generation (103)" ;
prov:wasQuotedFrom
pubmed:16870827
.
sub:_5
rdfs:label
"Selventa" .
sub:assertion
prov:hadPrimarySource
pubmed:16870827
;
prov:wasDerivedFrom
beldoc:
,
sub:_4
.
}
sub:pubinfo
{
this:
dct:created
"2014-07-03T14:33:02.442+02:00"^^
xsd:dateTime
;
pav:createdBy
orcid:0000-0001-6818-334X
,
orcid:0000-0002-1267-0234
.
}