http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_head http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_assertion http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_provenance http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_publicationInfo http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Assertion http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_provenance http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Provenance http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_publicationInfo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#PublicationInfo http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_assertion http://identifiers.org/ncbigene/338 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 http://linkedlifedata.com/resource/umls/id/C3272363 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057 http://rdf.disgenet.org/gene-disease-association.ttl#DGNc987445d02d5d76dc261025fd9f3be29 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/338 http://rdf.disgenet.org/gene-disease-association.ttl#DGNc987445d02d5d76dc261025fd9f3be29 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C3272363 http://rdf.disgenet.org/gene-disease-association.ttl#DGNc987445d02d5d76dc261025fd9f3be29 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001121 http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_provenance http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_assertion http://purl.org/dc/terms/description [The studies can be summarized as follows: (1) apolipoprotein B predicts ischemic cardiovascular events in both genders, and is better than LDL cholesterol in this respect; (2) linkage disequilibrium structure in APOB is more complex than expected from HapMap data, because a minimal set of tag single nucleotide polymorphisms capturing the entire variation in APOB cannot be identified, and thus most polymorphisms must be evaluated separately in association studies; (3) APOB mutations and polymorphisms are associated with a range of apolipoprotein B and LDL cholesterol levels, although the magnitude of effect sizes of common polymorphisms are modest; (4) both mutations and polymorphisms are associated with LDL metabolism in vivo; (5) association of APOB mutations and polymorphisms with lipid and disease phenotype cannot be predicted in silico using evolutionary conservation or existing prediction programs; and finally, (6) except for the E4154K polymorphism that possibly predicts a reduction in risk of ischemic cerebrovascular disease and ischemic stroke, common APOB polymorphisms with modest effect sizes on lipid levels do not predict risk of ischemic heart disease, myocardial infarction, ischemic cerebrovascular disease, or ischemic stroke in the general population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v2.1.0/void.ttl#source_evidence_literature http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/19200547 http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v2.1.0/void.ttl#befree-20140225 http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/eco.owl#ECO_0000203 http://rdf.disgenet.org/v2.1.0/void.ttl#befree-20140225 http://purl.org/pav/2.0/importedOn 2014-02-25 http://rdf.disgenet.org/v2.1.0/void.ttl#source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/eco.owl#ECO_0000212 http://rdf.disgenet.org/v2.1.0/void.ttl#source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v2.1.0/void.ttl#source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY130_publicationInfo http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/dc/terms/created 2014-10-02T12:41:14+02:00 http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v2.1.0/void.ttl#IBIGroup http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v2.1.0/void.ttl#disgenetrdf http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/pav/2.0/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/pav/2.0/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/pav/2.0/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/pav/2.0/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/pav/2.0/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/pav/2.0/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/nanopublications.trig#NP902630.RAmauU1fPHk1RiEmq9DzDt2GV7X_QKU40Lm-MZs-yEatY http://purl.org/pav/2.0/version v2.1.0.0 http://rdf.disgenet.org/v2.1.0/void.ttl#disgenetrdf http://purl.org/pav/2.0/version v2.1.0