http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#Head http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#assertion http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#provenance http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#pubinfo http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#assertion http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#_1 http://purl.obolibrary.org/obo/BFO_0000066 http://purl.obolibrary.org/obo/CL_0002618 http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#_1 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.ebi.ac.uk/chebi/searchId.do?chebiId=26523 http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://resource.belframework.org/belframework/20131211/namespace/selventa-legacy-chemicals/Oxidized%20Low%20Density%20Lipoprotein http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#assertion http://www.w3.org/2000/01/rdf-schema#label a(SCHEM:"Oxidized Low Density Lipoprotein") -> a(CHEBI:"reactive oxygen species") http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#_3 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#_2 http://www.w3.org/ns/prov#value After exposure to ox-LDL (50,100, and 150 microg/ml for 18 h), HUVECs exhibit typical apoptotic characteristics as determined by transmission electron microscopy and flow cytometry analysis in a dose-dependent pattern. Ox-LDL increases intracellular ROS formation including superoxide anion (O2-) and hydrogen peroxide (H2O2) in a dose-dependent and time-dependent manner. Pretreatment with anti-LOX-1 mAb, Vitamin C, apocynin or catalase significantly reduced ROS production and prevented ox-LDL-induced apoptosis, while indomethacin or allopurinol had no effect. http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#_2 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/17433786 http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#_3 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/17433786 http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#_2 http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU#pubinfo http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU http://purl.org/dc/terms/created 2014-07-03T14:33:10.106+02:00 http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAmYXYRg5vtcJiVdISEKJiFjyBuQa0T_HWMIevTC5_-mU http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234