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[Here, we summarize the recent findings that support the idea that the buildup of toxic RNA containing the GGGGCC repeat contributes to the death of motor neurons in ALS and also suggest that the use of antisense oligonucleotides targeting this transcript is a promising strategy for treating ALS/frontotemporal lobe dementia (FTLD) patients with the C9ORF72 repeat expansion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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