@prefix dct: <http://purl.org/dc/terms/> .
@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAm8DeTKgn9Az7XNl9k5EaINhwr5aABjvcRU9oVlQOGRI> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAm8DeTKgn9Az7XNl9k5EaINhwr5aABjvcRU9oVlQOGRI#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasPart: <http://purl.obolibrary.org/obo/BFO_0000051> .
@prefix ProteinComplex: <http://amigo.geneontology.org/amigo/term/GO:0043234> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix proteinModification: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000> .
@prefix psimod: <http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:> .
@prefix do: <http://disease-ontology.org/term/DOID:> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
   this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
   sub:_1 hasPart: sub:_2 , sub:_3 , sub:_4 ;
    a ProteinComplex: .
  sub:_2 geneProductOf: hgnc:6140 ;
    a Protein: .
  sub:_3 geneProductOf: hgnc:6134 ;
    a Protein: .
  sub:_4 geneProductOf: hgnc:9393 ;
    a Protein: .
  sub:_5 hasAgent: sub:_6 ;
    a go:0016301 .
  sub:_6 geneProductOf: hgnc:9393 ;
    a Protein: .
  sub:_7 belv:variantOf hgnc:6140 ;
    a proteinModification: , psimod:00696 .
  sub:_8 rdf:object sub:_7 ;
    rdf:predicate belv:directlyIncreases ;
    rdf:subject sub:_5 ;
    a rdf:Statement .
  sub:_9 occursIn: do:9538 , species:9606 ;
    rdf:object sub:_8 ;
    rdf:predicate belv:directlyIncreases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "complex(p(HGNC:ITGA4),p(HGNC:ITGA1),p(HGNC:PRKCA)) => (kin(p(HGNC:PRKCA)) => p(HGNC:ITGA4,pmod(P)))" , "kin(p(HGNC:PRKCA)) => p(HGNC:ITGA4,pmod(P))" .
}
sub:provenance {
   beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_11 ;
    pav:version "20131211" .
  sub:_10 prov:value "PKCa Associates with b1 Integrin and CADTK...We therefore next determined whether PKCa and b1 integrin are associated in MM cells. Constitutive complex formation between these two proteins was demonstrated by co-immunoprecipitation...Upon activation and translocation, conventional PKCs associate with proteins of the transmembrane-4 superfamily (TM4SF or tetraspans) linking PKC to several subsets of integrins (38) including a4b1 (39) and a5b1...the integrin-TM4SF-PKC complex formation results in phosphorylation of the integrin alpha cytoplasmic tail" ;
    prov:wasQuotedFrom pubmed:11751905 .
  sub:_11 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:11751905 ;
    prov:wasDerivedFrom beldoc: , sub:_10 .
}
sub:pubinfo {
   this: dct:created "2014-07-03T14:31:45.563+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}