@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v4.0.0/void/> .

dgn-np:NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc130_head {
  this: np:hasAssertion dgn-np:NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc130_assertion;
    np:hasProvenance dgn-np:NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc130_provenance;
    np:hasPublicationInfo dgn-np:NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc130_assertion a np:Assertion .
  
  dgn-np:NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc130_provenance a np:Provenance .
  
  dgn-np:NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc130_publicationInfo
    a np:PublicationInfo .
}

dgn-np:NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc130_assertion {
  miriam-gene:3169 a ncit:C16612 .
  
  lld:C1458155 a ncit:C7057 .
  
  dgn-gda:DGNe3d43cc4276a23a666aa440f1105ea20 sio:SIO_000628 miriam-gene:3169, lld:C1458155;
    a sio:SIO_001121 .
}

dgn-np:NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc130_provenance {
  dgn-np:NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc130_assertion dcterms:description
      "[Integrated analysis of the global gene methylation and expression profiles of a set of 33 familial breast tumours revealed that FOXA1 promoter methylation is inversely correlated with the transcriptional expression of FOXA1 and that BRCA1 mutation breast cancer is significantly associated with FOXA1 methylation and downregulation of FOXA1 expression, providing physiological evidence to our findings that FOXA1 expression is regulated by methylation and chromatin silencing and that BRCA1 maintains FOXA1 expression through suppressing FOXA1 gene methylation in breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:25531315;
    prov:wasDerivedFrom dgn-void:befree-2016;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP1250284.RAlVIEhUuCyFCHvnu81V_BqriPAOKrBlhuwBS7QMBcIcc130_publicationInfo {
  this: dcterms:created "2016-05-13T12:51:12+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v4.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v4.0.0" .
}