http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#Head http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY http://www.nanopub.org/nschema#hasAssertion http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#assertion http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY http://www.nanopub.org/nschema#hasProvenance http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#provenance http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY http://www.nanopub.org/nschema#hasPublicationInfo http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#pubinfo http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#assertion http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_1 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_2 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_1 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0003824 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_2 http://purl.obolibrary.org/obo/RO_0002204 http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=9052 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_2 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_3 http://semanticscience.org/resource/SIO_000139 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_4 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_3 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://amigo.geneontology.org/amigo/term/GO:0003824 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_4 http://purl.obolibrary.org/obo/RO_0002204 http://resource.belframework.org/belframework/20131211/namespace/selventa-protein-families/MMP%20Family http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_4 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_5 http://purl.obolibrary.org/obo/BFO_0000066 http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#object http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_3 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate http://www.selventa.com/vocabulary/increases http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#subject http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_1 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_5 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#assertion http://www.w3.org/2000/01/rdf-schema#label cat(p(HGNC:PLAU)) -> cat(p(SFAM:"MMP Family")) http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#provenance http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/description Approximately 61,000 statements. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/rights Copyright (c) 2011-2012, Selventa. All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_7 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_6 http://www.w3.org/ns/prov#value Both uPA itself and uPA-generated plasmin can activate the latent matrix metalloproteinases and elastase [46, 148], which are responsible for the subsequent degradation of the extracellular matrix, during the endothelial cell migration and invasion. Moreover these two proteases activate virtually all growth factors involved in angiogenesis [42-45, 147, 149]. Hypoxia has been shown to increase the expression of angiogenic growth factors, but uPA and plasmin are required to provide proteolytic activation of the latent forms or release of matrix-bound growth factors. http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11841347 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11841347 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#_6 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY#pubinfo http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY http://purl.org/dc/terms/created 2014-07-03T14:31:46.898+02:00 http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAlTztsLlLenoy1n5ULDrXn4oSU8UhVG88L9jR8scPodY http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234