sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    
dce:title "BEL Framework Large Corpus Document" ;
    
pav:authoredBy sub:_5 ;
    
pav:version "1.4" . 
  
sub:_4 prov:value "(from text) We confirmed this essential role for huntingtin on our arrays, detecting the general down-regulation of genes involved in growth, proliferation and cellular differentiation (Fig. 6). A subset of these transcripts appear to function specifically within the brain: Serpinf1, Emp3, Tcfap2c, Dlx3 and Elavl4. Many general growth-related or mitogenic mRNAs (Ghrh, Scgb3a1, Cdkn1c, Sp6, Gkn1, Igf2) also exhibited reduced expression. Conversely, Hdh null neurons consistently overexpressed Ccng2, a negative regulator of cell proliferation and cell cycle progression." ;
    
prov:wasQuotedFrom pubmed:17189290 . 
  
sub:_5 rdfs:label "Selventa" . 
  
sub:assertion prov:hadPrimarySource pubmed:17189290 ;
    
prov:wasDerivedFrom beldoc: , 
sub:_4 . 
}