. . . . . . . . . . . . . . "cat(p(HGNC:CYP2E1)) -> a(CHEBI:\"reactive oxygen species\")" . "Approximately 61,000 statements." . "Copyright (c) 2011-2012, Selventa. All rights reserved." . "BEL Framework Large Corpus Document" . . "20131211" . "PI3-kinase/AKT may serve as a survival pathway against CYP2E1-dependent toxicity.E47 cells (HepG2 cells transfected with human CYP2E1 cDNA) exposed to 25 microM iron-nitrilotriacetate+5 microM arachidonic acid (AA+Fe) developed higher toxicity than C34 cells (HepG2 cells transfected with empty plasmid). Toxicity was associated with increased oxidative stress and activation of calcium-dependent hydrolases calpain and phospholipase A2." . . "Selventa" . . . . "2014-07-03T14:32:59.850+02:00"^^ . . .