@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP814984.RAl86hY1E3hR4603sPZGZBrHqMBi8GVl7dFh45wJf7afY> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .
dgn-np:NP814984.RAl86hY1E3hR4603sPZGZBrHqMBi8GVl7dFh45wJf7afY130_head {
   this: np:hasAssertion dgn-np:NP814984.RAl86hY1E3hR4603sPZGZBrHqMBi8GVl7dFh45wJf7afY130_assertion ;
    np:hasProvenance dgn-np:NP814984.RAl86hY1E3hR4603sPZGZBrHqMBi8GVl7dFh45wJf7afY130_provenance ;
    np:hasPublicationInfo dgn-np:NP814984.RAl86hY1E3hR4603sPZGZBrHqMBi8GVl7dFh45wJf7afY130_publicationInfo ;
    a np:Nanopublication .
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  dgn-np:NP814984.RAl86hY1E3hR4603sPZGZBrHqMBi8GVl7dFh45wJf7afY130_provenance a np:Provenance .
  dgn-np:NP814984.RAl86hY1E3hR4603sPZGZBrHqMBi8GVl7dFh45wJf7afY130_publicationInfo a np:PublicationInfo .
}
dgn-np:NP814984.RAl86hY1E3hR4603sPZGZBrHqMBi8GVl7dFh45wJf7afY130_assertion {
   miriam-gene:1636 a ncit:C16612 .
  lld:C0854193 a ncit:C7057 .
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    a sio:SIO_001121 .
}
dgn-np:NP814984.RAl86hY1E3hR4603sPZGZBrHqMBi8GVl7dFh45wJf7afY130_provenance {
   dgn-np:NP814984.RAl86hY1E3hR4603sPZGZBrHqMBi8GVl7dFh45wJf7afY130_assertion dcterms:description "[With diverse multifactorial therapies, combining different types of drugs and metabolic factors, it is partially possible to slow-down cognitive deterioration, improving non-cognitive symptoms, such as anxiety and depression, which currently aggravate cognition and increase the difficulties in disease management; however, the association of the APOE-4 allele with specific genetic variants of other genes (e.g., CYP2D6, ACE) negatively modulate the therapeutic response to multifactorial treatments affecting cognition, mood and behaviour.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en ;
    wi:evidence dgn-void:source_evidence_literature ;
    sio:SIO_000772 miriam-pubmed:17957277 ;
    prov:wasDerivedFrom dgn-void:befree-20140225 ;
    prov:wasGeneratedBy eco:ECO_0000203 .
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  dgn-void:source_evidence_literature a eco:ECO_0000212 ;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en ;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}
dgn-np:NP814984.RAl86hY1E3hR4603sPZGZBrHqMBi8GVl7dFh45wJf7afY130_publicationInfo {
   this: dcterms:created "2014-10-02T12:40:19+02:00"^^xsd:dateTime ;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/> ;
    dcterms:rightsHolder dgn-void:IBIGroup ;
    dcterms:subject sio:SIO_000983 ;
    prv:usedData dgn-void:disgenetrdf ;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269> , <http://orcid.org/0000-0002-7534-7661> , <http://orcid.org/0000-0002-9383-528X> , <http://orcid.org/0000-0003-0169-8159> , <http://orcid.org/0000-0003-1244-7654> ;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159> ;
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}