@prefix dcterms: .
@prefix this: .
@prefix sub: .
@prefix beldoc: .
@prefix rdfs: .
@prefix rdf: .
@prefix xsd: .
@prefix dce: .
@prefix pav: .
@prefix np: .
@prefix belv: .
@prefix prov: .
@prefix Protein: .
@prefix hgnc: .
@prefix geneProductOf: .
@prefix schem: .
@prefix go: .
@prefix hasAgent: .
@prefix species: .
@prefix occursIn: .
@prefix mesh: .
@prefix pubmed: .
@prefix orcid: .
sub:Head {
this: np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo;
a np:Nanopublication .
}
sub:assertion {
sub:_1 geneProductOf: hgnc:14565;
a Protein: .
sub:_2 hasAgent: sub:_3;
a go:0003824 .
sub:_3 geneProductOf: hgnc:17736;
a Protein: .
sub:_4 rdf:object sub:_2;
rdf:predicate belv:increases;
rdf:subject schem:serum%20insulin;
a rdf:Statement .
sub:_5 occursIn: mesh:D002462, mesh:D009132, species:9606;
rdf:object sub:_4;
rdf:predicate belv:increases;
rdf:subject sub:_1;
a rdf:Statement .
sub:assertion rdfs:label "a(SCHEM:\"serum insulin\") -> cat(p(HGNC:RHOQ))", "p(HGNC:SORBS1) -> (a(SCHEM:\"serum insulin\") -> cat(p(HGNC:RHOQ)))" .
}
sub:provenance {
beldoc: dce:description "Approximately 61,000 statements.";
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
dce:title "BEL Framework Large Corpus Document";
pav:authoredBy sub:_7;
pav:version "1.4" .
sub:_6 prov:value "Once phosphorylated, Cbl can recruit the SH2-containing adaptor protein CrkII to lipid rafts, along with the GEF C3G. C3G then appears to activate the Rho family GTPase TC10. This small GTP-binding protein is produced in fat and muscle and can be acutely activated by insulin in a CAP-dependent but PdtIns-3-kinase-independent manner. Activation of TC10 is specific for insulin, and disruption of its activation blocks insulin-stimulated glucose transport and Glut4 translocation.";
prov:wasQuotedFrom pubmed:11849969 .
sub:_7 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:11849969;
prov:wasDerivedFrom beldoc:, sub:_6 .
}
sub:pubinfo {
this: dcterms:created "2014-07-03T14:30:01.094+02:00"^^xsd:dateTime;
pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}