@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v3.0.0/void/> .

dgn-np:NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M130_head {
  this: np:hasAssertion dgn-np:NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M130_assertion;
    np:hasProvenance dgn-np:NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M130_provenance;
    np:hasPublicationInfo dgn-np:NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M130_assertion a np:Assertion .
  
  dgn-np:NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M130_provenance a np:Provenance .
  
  dgn-np:NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M130_assertion {
  miriam-gene:2224 a ncit:C16612 .
  
  lld:C0877008 a ncit:C7057 .
  
  dgn-gda:DGNb3b38b6cb7c975120ad8696d9462395b sio:SIO_000628 miriam-gene:2224, lld:C0877008;
    a sio:SIO_001121 .
}

dgn-np:NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M130_provenance {
  dgn-np:NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M130_assertion dcterms:description
      "[The target of all of the most active bisphosphonates appears to be the isoprene biosynthesis pathway enzyme farnesyl pyrophosphate synthase (FPPS), as indicated by the correlations between T. gondii growth inhibition and FPPS (human and Leishmania major) enzyme inhibition and by the fact that a T. gondii strain engineered to overexpress FPPS required considerably higher levels of bisphosphonates to achieve 50% growth inhibition, while the IC(50) for atovaquone (which does not inhibit FPPS) remained the same in the overexpressing strain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:15857119;
    prov:wasDerivedFrom dgn-void:befree-20150227;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20150227 pav:importedOn "2015-02-27"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP397773.RAkeaQ3hZA_f_ixxgwQNNmNqofS7UCVJ80zOTI-CNF63M130_publicationInfo {
  this: dcterms:created "2015-08-25T14:41:31+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v3.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v3.0.0" .
}