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[Taking a broad-based approach by using a number of small-molecule inhibitors of various mitogenic/survival pathways, we found that only treatment of non-small cell lung cancer (NSCLC) cell lines with the phosphoinositide 3-kinase (PI3K) inhibitor LY294002 (50 ?mol/L) or the pan-protein kinase C (PKC) inhibitor G�6983 (25 ?mol/L) decreased the Bcl-x(L)/(s) mRNA ratio.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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