@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAkTdQLx0eyIIQdjUZ2rpS3Trya4cu0RHSRTfMIg7OqvM> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAkTdQLx0eyIIQdjUZ2rpS3Trya4cu0RHSRTfMIg7OqvM#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .

sub:Head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:pubinfo;
    a np:Nanopublication .
}

sub:assertion {
  sub:_1 geneProductOf: hgnc:1785;
    a Protein: .
  
  sub:_2 hasAgent: sub:_3;
    a go:0016301 .
  
  sub:_3 geneProductOf: hgnc:1778;
    a Protein: .
  
  sub:_4 hasAgent: sub:_5;
    a go:0016301 .
  
  sub:_5 geneProductOf: hgnc:1771;
    a Protein: .
  
  sub:_6 rdf:object sub:_4;
    rdf:predicate belv:increases;
    rdf:subject sub:_2;
    a rdf:Statement .
  
  sub:_7 occursIn: obo:CL_0000057, species:9606;
    rdf:object sub:_6;
    rdf:predicate belv:decreases;
    rdf:subject sub:_1;
    a rdf:Statement .
  
  sub:assertion rdfs:label "kin(p(HGNC:CDK7)) -> kin(p(HGNC:CDK2))", "p(HGNC:CDKN1B) -| (kin(p(HGNC:CDK7)) -> kin(p(HGNC:CDK2)))" .
}

sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements.";
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
    dce:title "BEL Framework Large Corpus Document";
    pav:authoredBy sub:_9;
    pav:version "20131211" .
  
  sub:_8 prov:value "Phosphorylation of cyclin-dependent kinases (CDKs) by the CDK-activating kinase is required for the activation of CDK enzymes. Members of two families of CDK inhibitors, p16/p18 and p21/p27, become physically associated with and inhibit the activity of CDKs in response to a variety of growth-modulating signals. Here, we show that the representative members of both families of CDK inhibitors, p21waf1,cip1, p27kip1, and p18, can prevent the phosphorylation of their CDK partners, CDK2 and CDK6, by CDK-activating kinase.";
    prov:wasQuotedFrom pubmed:7629134 .
  
  sub:_9 rdfs:label "Selventa" .
  
  sub:assertion prov:hadPrimarySource pubmed:7629134;
    prov:wasDerivedFrom beldoc:, sub:_8 .
}

sub:pubinfo {
  this: dct:created "2014-07-03T14:33:45.814+02:00"^^xsd:dateTime;
    pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}