@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v4.0.0/void/> .

dgn-np:NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw130_head {
  this: np:hasAssertion dgn-np:NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw130_assertion;
    np:hasProvenance dgn-np:NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw130_provenance;
    np:hasPublicationInfo dgn-np:NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw130_assertion a np:Assertion .
  
  dgn-np:NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw130_provenance a np:Provenance .
  
  dgn-np:NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw130_publicationInfo
    a np:PublicationInfo .
}

dgn-np:NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw130_assertion {
  miriam-gene:3845 a ncit:C16612 .
  
  lld:C0600139 a ncit:C7057 .
  
  dgn-gda:DGNdde49b9a53e19c114a48d64735f64cf0 sio:SIO_000628 miriam-gene:3845, lld:C0600139;
    a sio:SIO_001121 .
}

dgn-np:NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw130_provenance {
  dgn-np:NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw130_assertion dcterms:description
      "[It is increasingly clear that there are molecularly distinct subtypes of various common cancers, with different therapeutic approaches required for each subtype, for example, the use of the monoclonal antibodies (trastuzumab and cetuximab) in HER2-positive breast cancer and wild-type KRAS colorectal cancer; tyrosine kinase inhibitors (imatinib, gefitinib, erlotinib and crizotinib) in chronic myeloid leukaemia, gastrointestinal stromal tumours and non-small-cell lung cancer and intracellular agents (vemurafenib and olaparib) in metastatic malignant melanoma and ovarian, breast and prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:24789362;
    prov:wasDerivedFrom dgn-void:befree-2016;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP1178756.RAkGrTXg6fsEPyP50Pw7H6Q2UlBc2Zwg9l3L9kR8yjncw130_publicationInfo {
  this: dcterms:created "2016-05-13T12:50:40+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v4.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v4.0.0" .
}