http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#head http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#assertion http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#provenance http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#assertion http://rdf.disgenet.org/resource/gda/DGNed19d732b7ebb04568934fa47fc0f002 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/11167 http://rdf.disgenet.org/resource/gda/DGNed19d732b7ebb04568934fa47fc0f002 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0004135 http://rdf.disgenet.org/resource/gda/DGNed19d732b7ebb04568934fa47fc0f002 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001122 http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#provenance http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#assertion http://purl.org/dc/terms/description [Here, using pair-matched wild-type p53 CDDP-sensitive (OV2008) and -resistant (C13*) cells, and p53-compromised CDDP-resistant cells (A2780cp, OCC-1, OVCAR-3 and SKOV3), we have demonstrated (i) the existence of site-specific differences in phospho-Ser-Chk1 content between sensitive and resistant cells in response to CDDP; (ii) PPM1D, but not phosphoinositide-3-kinase-related kinase Ataxia Telangiectasia and Rad3 related protein (ATR), is important in the regulation of CDDP-induced Chk1 activation and OVCA cell chemosensitivity; (iii) PPM1D downregulation sensitizes resistant cells to CDDP primarily by activating Chk1 and p53.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/21927021 http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v5.0.0/void/BEFREE http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v5.0.0/void/BEFREE http://purl.org/pav/importedOn 2017-02-19 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/dc/terms/created 2017-10-17T13:18:06+02:00 http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v5.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP1241645.RAjv_41Da2S9Fy_yHMtbmCisfkq-NPVr_h4bJVaQi-zpM http://purl.org/pav/version v5.0.0.0 http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v5.0.0