@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v4.0.0/void/> .

dgn-np:NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4130_head {
  this: np:hasAssertion dgn-np:NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4130_assertion;
    np:hasProvenance dgn-np:NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4130_provenance;
    np:hasPublicationInfo dgn-np:NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4130_assertion a np:Assertion .
  
  dgn-np:NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4130_provenance a np:Provenance .
  
  dgn-np:NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4130_publicationInfo
    a np:PublicationInfo .
}

dgn-np:NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4130_assertion {
  miriam-gene:6778 a ncit:C16612 .
  
  lld:C0268800 a ncit:C7057 .
  
  dgn-gda:DGN74d31778a782f2c86873a21f7d7f1634 sio:SIO_000628 miriam-gene:6778, lld:C0268800;
    a sio:SIO_001121 .
}

dgn-np:NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4130_provenance {
  dgn-np:NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4130_assertion dcterms:description
      "[Using human ADPKD tissues and polycystic kidney disease mouse models, we show that the polymeric immunoglobulin receptor (pIgR) is highly expressed by renal cyst-lining cells. pIgR expression is, in part, driven by aberrant STAT6 pathway activation. pIgR actively transports dIgA from the circulation across the cyst epithelium and releases it into the cyst lumen as secretory IgA. dIgA administered by intraperitoneal injection is preferentially targeted to polycystic kidneys whereas injected IgG is not.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:25922073;
    prov:wasDerivedFrom dgn-void:befree-2016;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP1281243.RAjeDihgYt7JtgdG8XIYwqtCwAjIWygWp03Ubg3NcXLM4130_publicationInfo {
  this: dcterms:created "2016-05-13T12:51:27+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v4.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v4.0.0" .
}