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All rights reserved. http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE#_4 http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://purl.org/pav/version 1.4 http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE#_3 http://www.w3.org/ns/prov#value TABLE 2. Comprehensive list of insulin signaling genes analyzed by microarray. from text - SAM analysis was performed on SC and OM samples separately using the same analysis parameters. With an estimated FDR of 0.5% and a minimum 3-fold change, 941 genes were identified as significantly different in OM tissue comparing IRO and ISO + NO. Using the same analysis parameters, no genes were identified as significantly different in SC tissue comparing IRO and ISO + NO. Using less stringent criteria (FDR = 15% and minimum 3-fold change), 534 genes were identified. When gene expression in OM tissue was compared directly with that in SC tissue, using paired analysis and the stringent parameters (0.5% FDR and minimum 3-fold difference), no genes were identified. Using less stringent criteria (FDR = 5% and minimum 2-fold change), only 48 significant genes were identified. Therefore, by far, the major differences in gene expression in this sample set appear to be the differences related to insulin sensitivity in OM tissue (IRO vs. ISO + NO). http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE#_3 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/17986714 http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE#_4 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/17986714 http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE#_3 http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE#pubinfo http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE http://purl.org/dc/terms/created 2014-07-03T14:30:52.209+02:00 http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAjZRw3eC4HI-smJI3uR7W-f4zgA5TPRf7ysFLL1UuMKE http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234