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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE#_7 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE#_6 http://www.w3.org/ns/prov#value (from text) These experiments demonstrated that GATA3 binds the palindromic FOXP3 promoter. To gain insights into the in vivo situation, we performed a chromatin immunoprecipitation (ChIP) using an anti-GATA3 antibody and showed that GATA3 binds to the FOXP3 promoter region in Th2 cells, but not in iTreg cells (Figure 7F). Taken together these data demonstrate that the GATA3-binding to the FOXP3 promoter is repressing FOXP3 expression. http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/18162042 http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/18162042 http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE#_6 http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE#pubinfo http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE http://purl.org/dc/terms/created 2014-07-03T14:33:14.262+02:00 http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAjYdb8DR0AuOAXzUbjcEUWPksMHuInqcIngJ9BPtGciE http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234