@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP1354008.RAjVY8SvLnWn5Vqi1kUaSBpkf80DlmxzZDDYjjDdYlWLk130_head { this: np:hasAssertion dgn-np:NP1354008.RAjVY8SvLnWn5Vqi1kUaSBpkf80DlmxzZDDYjjDdYlWLk130_assertion; np:hasProvenance dgn-np:NP1354008.RAjVY8SvLnWn5Vqi1kUaSBpkf80DlmxzZDDYjjDdYlWLk130_provenance; np:hasPublicationInfo dgn-np:NP1354008.RAjVY8SvLnWn5Vqi1kUaSBpkf80DlmxzZDDYjjDdYlWLk130_publicationInfo; a np:Nanopublication . dgn-np:NP1354008.RAjVY8SvLnWn5Vqi1kUaSBpkf80DlmxzZDDYjjDdYlWLk130_assertion a np:Assertion . dgn-np:NP1354008.RAjVY8SvLnWn5Vqi1kUaSBpkf80DlmxzZDDYjjDdYlWLk130_provenance a np:Provenance . dgn-np:NP1354008.RAjVY8SvLnWn5Vqi1kUaSBpkf80DlmxzZDDYjjDdYlWLk130_publicationInfo a np:PublicationInfo . } dgn-np:NP1354008.RAjVY8SvLnWn5Vqi1kUaSBpkf80DlmxzZDDYjjDdYlWLk130_assertion { miriam-gene:5020 a ncit:C16612 . lld:C0032002 a ncit:C7057 . dgn-gda:DGN233fa1a7d74e9813da3288e91170c058 sio:SIO_000628 miriam-gene:5020, lld:C0032002; a sio:SIO_001123 . } dgn-np:NP1354008.RAjVY8SvLnWn5Vqi1kUaSBpkf80DlmxzZDDYjjDdYlWLk130_provenance { dgn-np:NP1354008.RAjVY8SvLnWn5Vqi1kUaSBpkf80DlmxzZDDYjjDdYlWLk130_assertion dcterms:description "[Multiple lines of evidence now support this hypothesis: 1) intracerebroventricular (icv) OT administration inhibits food intake in fasted rats and NaCl intake in hypovolemic rats; 2) icv administration of OT-receptor antagonists significantly blunts the effects of anorexigenic agents on food intake and the action of naloxone to inhibit hypovolemia-induced intake of NaCl, but not water; 3) most treatments that inhibit food and/or NaCl intake stimulate expression of c-fos in parvocellular as well as magnocellular OT neurons, indicating simultaneous activation of both centrally-projecting and pituitary-projecting OT neurons; 4) icv treatment with cytotoxic conjugates of ricin A and OT to disable cells bearing OT receptors leads to a disinhibition of NaCl intake similar to that produced by OT antagonists; 5) administration of ethanol, a well known inhibitor of OT secretion, produces effects on stimulated food and NaCl intake in rats analogous to those produced by OT-antagonists and ricin-OT conjugates.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:8713970; prov:wasDerivedFrom dgn-void:befree-2016; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP1354008.RAjVY8SvLnWn5Vqi1kUaSBpkf80DlmxzZDDYjjDdYlWLk130_publicationInfo { this: dcterms:created "2016-05-13T12:52:00+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetv3.0rdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v4.0.0.0" . dgn-void:disgenetv3.0rdf pav:version "v4.0.0" . }