@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v4.0.0/void/> .
dgn-np:NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc130_head {
   this: np:hasAssertion dgn-np:NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc130_assertion ;
    np:hasProvenance dgn-np:NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc130_provenance ;
    np:hasPublicationInfo dgn-np:NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc130_publicationInfo ;
    a np:Nanopublication .
  dgn-np:NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc130_assertion a np:Assertion .
  dgn-np:NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc130_provenance a np:Provenance .
  dgn-np:NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc130_publicationInfo a np:PublicationInfo .
}
dgn-np:NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc130_assertion {
   miriam-gene:4851 a ncit:C16612 .
  lld:C0686619 a ncit:C7057 .
  dgn-gda:DGN8e93d3c25d00612d91b44bff6e9cd343 sio:SIO_000628 miriam-gene:4851 , lld:C0686619 ;
    a sio:SIO_001121 .
}
dgn-np:NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc130_provenance {
   dgn-np:NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc130_assertion dcterms:description "[(Mech Dev, 98, 2000, 95) Notch 1-4 are up-regulated in NSCLC tissues and Notch 1, 2 are positively correlated with lymph node metastasis, (Proc Natl Acad Sci U S A, 106, 2009, 22293) DAPT treatment could inhibit NRSP and induce apoptosis, with a marked increase in cleaved PARP, decreases in XIAP and Survivin proteins and concomitant release of Smac, EndoG, and AIF from mitochondria, indicating that inhibiting NRSP by DAPT triggers caspase-dependent and caspase-independent apoptosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en ;
    wi:evidence dgn-void:source_evidence_literature ;
    sio:SIO_000772 miriam-pubmed:22583356 ;
    prov:wasDerivedFrom dgn-void:befree-2016 ;
    prov:wasGeneratedBy eco:ECO_0000203 .
  dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date .
  dgn-void:source_evidence_literature a eco:ECO_0000212 ;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en ;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}
dgn-np:NP981957.RAjJsbQZzJ_x-b6mTZ4dRgP5tmN7wYRGsmzOWklxVDHIc130_publicationInfo {
   this: dcterms:created "2016-05-13T12:49:10+02:00"^^xsd:dateTime ;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/> ;
    dcterms:rightsHolder dgn-void:IBIGroup ;
    dcterms:subject sio:SIO_000983 ;
    prv:usedData dgn-void:disgenetv3.0rdf ;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269> , <http://orcid.org/0000-0002-7534-7661> , <http://orcid.org/0000-0002-9383-528X> , <http://orcid.org/0000-0003-0169-8159> , <http://orcid.org/0000-0003-1244-7654> ;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159> ;
    pav:version "v4.0.0.0" .
  dgn-void:disgenetv3.0rdf pav:version "v4.0.0" .
}