sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_6 ; pav:version "20131211" . sub:_5prov:value "Although the evidence implicating Egr-1 in IMPDH type II expression is circumstantial at present, the presence of a protected region (C) corresponding to the Egr-1 binding site in the IMPDH type II promoter and the requirement for increased IMPDH gene expression for T lymphocyte activation do suggest that this site could be of considerable functional importance. It has been observed, for example, that Egr-1 can act as a repressor of Sp1 activity at the coincident binding site in the adenosine deaminase gene promoter" ; prov:wasQuotedFrompubmed:7896827 . sub:_6rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcepubmed:7896827 ; prov:wasDerivedFrombeldoc: , sub:_5 . }