@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v3.0.0/void/> .

dgn-np:NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U130_head {
  this: np:hasAssertion dgn-np:NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U130_assertion;
    np:hasProvenance dgn-np:NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U130_provenance;
    np:hasPublicationInfo dgn-np:NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U130_assertion a np:Assertion .
  
  dgn-np:NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U130_provenance a np:Provenance .
  
  dgn-np:NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U130_assertion {
  miriam-gene:1514 a ncit:C16612 .
  
  lld:C0007097 a ncit:C7057 .
  
  dgn-gda:DGN5e2d39abdd2d37b68d2d35e18b08ff90 sio:SIO_000628 miriam-gene:1514, lld:C0007097;
    a sio:SIO_001121 .
}

dgn-np:NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U130_provenance {
  dgn-np:NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U130_assertion dcterms:description
      "[To determine whether primary cancers also demonstrate higher cysteine proteinase activities in the presence of activated ras genes or altered ras protein expression, we have analyzed 60 primary human colorectal carcinomas for ras gene or protein changes together with the expression of cathepsins B and L. Cancers containing K-ras mutations (47% of 60 carcinomas) demonstrated greater increases in cathepsin L activity than cancers without K-ras mutations (p = 0.029), with particularly significant correlations for earlier stage cancers (Dukes' A and B carcinomas, p = 0.006).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:9699522;
    prov:wasDerivedFrom dgn-void:befree-20150227;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20150227 pav:importedOn "2015-02-27"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP337778.RAjBnX7aV_Y2TYx5uRgQDD095M1TuclwgLwSnkF0WfW5U130_publicationInfo {
  this: dcterms:created "2015-08-25T14:40:54+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v3.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v3.0.0" .
}