@prefix this: . @prefix sub: . @prefix beldoc: . @prefix rdfs: . @prefix rdf: . @prefix xsd: . @prefix dct: . @prefix dce: . @prefix pav: . @prefix np: . @prefix belv: . @prefix prov: . @prefix Protein: . @prefix rgd: . @prefix geneProductOf: . @prefix RNA: . @prefix species: . @prefix occursIn: . @prefix obo: . @prefix pubmed: . @prefix orcid: . sub:Head { this: np:hasAssertion sub:assertion; np:hasProvenance sub:provenance; np:hasPublicationInfo sub:pubinfo; a np:Nanopublication . } sub:assertion { sub:_1 geneProductOf: rgd:1598328; a Protein: . sub:_2 geneProductOf: rgd:2544; a RNA: . sub:_3 occursIn: obo:CLO_0008392, species:10116; rdf:object sub:_2; rdf:predicate belv:increases; rdf:subject sub:_1; a rdf:Statement . sub:assertion rdfs:label "p(RGD:Ngf) -> r(RGD:Egr1)" . } sub:provenance { beldoc: dce:description "Approximately 61,000 statements."; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved."; dce:title "BEL Framework Large Corpus Document"; pav:authoredBy sub:_5; pav:version "20131211" . sub:_4 prov:value "The presence of a consensus binding site (CGCCCCCGC) for the transcription factor Egr-1 (synonymous with Krox-24, NGFI-A, Zif268, and TIS-8) at bp -163 is particularly notable. This site has been shown to bind a family of zinc finger proteins that are immediate early response genes important in growth regulation. Egr-1 expression is rapidly and transiently induced by nerve growth factor in PC12 cells and by serum in fibroblasts. Of particular relevance is the observation that Egr-1 is induced during the G/G transition in the cell cycle after mitogenic stimulation of T lymphocytes, as well as during G as a separate event mediated by interleukin-2."; prov:wasQuotedFrom pubmed:7896827 . sub:_5 rdfs:label "Selventa" . sub:assertion prov:hadPrimarySource pubmed:7896827; prov:wasDerivedFrom beldoc:, sub:_4 . } sub:pubinfo { this: dct:created "2014-07-03T14:33:47.088+02:00"^^xsd:dateTime; pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 . }