http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_head http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_assertion http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_provenance http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_assertion http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Assertion http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_provenance http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Provenance http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_publicationInfo http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#PublicationInfo http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_assertion http://identifiers.org/ncbigene/7855 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C16612 http://linkedlifedata.com/resource/umls/id/C1306459 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C7057 http://rdf.disgenet.org/resource/gda/DGN4170d366f5d87377a240a5d02311aa60 http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/7855 http://rdf.disgenet.org/resource/gda/DGN4170d366f5d87377a240a5d02311aa60 http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C1306459 http://rdf.disgenet.org/resource/gda/DGN4170d366f5d87377a240a5d02311aa60 http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001121 http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_provenance http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_assertion http://purl.org/dc/terms/description [The low cancer incidence in the epididymis may be due to factors present in the human epididymis that regulate this oncogenic Wnt/β-catenin pathway, including (i) 14 of 17 secreted pathway inhibitors, (ii) the majority of the micro-RNAs known to target this pathway, (iii) plasma membrane-associated E-cadherin and CEACAM1 that anchor β-catenin, preventing its availability for nuclear entry and oncogenic transcriptional activity, (iv) the recently identified membrane-located tumourigenesis inhibitors RNF43 and ZNRF3 that mediate the degradation of the Wnt receptor components Fzds and Lrp5/6 and (v) nuclear KLF4, which competes with TCF for β-catenin, limiting its transcriptional activity and stabilizing telomeres, thereby reducing mutation incidence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/23155044 http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v3.0.0/void/befree-20150227 http://purl.org/pav/importedOn 2015-02-27 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v3.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo130_publicationInfo http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/dc/terms/created 2015-08-25T14:45:35+02:00 http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v3.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP785423.RAi7Mfp3-cGJYQb6kLaRWkI8_rY04d7RwOFFRZ-YzyLmo http://purl.org/pav/version v3.0.0.0 http://rdf.disgenet.org/v3.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v3.0.0