@prefix this: <http://www.tkuhn.ch/bel2nanopub/RAi2vcqvzdIXJp1IHasBqltUVxQa6ue74--q0uOfxXNuM> .
@prefix sub: <http://www.tkuhn.ch/bel2nanopub/RAi2vcqvzdIXJp1IHasBqltUVxQa6ue74--q0uOfxXNuM#> .
@prefix beldoc: <http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix dce: <http://purl.org/dc/elements/1.1/> .
@prefix pav: <http://purl.org/pav/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix belv: <http://www.selventa.com/vocabulary/> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix go: <http://amigo.geneontology.org/amigo/term/GO:> .
@prefix Protein: <http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080> .
@prefix hgnc: <http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=> .
@prefix geneProductOf: <http://purl.obolibrary.org/obo/RO_0002204> .
@prefix hasAgent: <http://semanticscience.org/resource/SIO_000139> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix occursIn: <http://purl.obolibrary.org/obo/BFO_0000066> .
@prefix species: <http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=> .
@prefix pubmed: <http://www.ncbi.nlm.nih.gov/pubmed/> .
@prefix orcid: <http://orcid.org/> .
sub:Head {
  this: np:hasAssertion sub:assertion ;
    np:hasProvenance sub:provenance ;
    np:hasPublicationInfo sub:pubinfo ;
    a np:Nanopublication .
}
sub:assertion {
  sub:_1 hasAgent: sub:_2 ;
    a go:0003824 .
  sub:_2 geneProductOf: hgnc:7562 ;
    a Protein: .
  sub:_3 hasAgent: sub:_4 ;
    a go:0016301 .
  sub:_4 geneProductOf: hgnc:6112 ;
    a Protein: .
  sub:_5 occursIn: obo:CL_0002328 , species:9606 ;
    rdf:object sub:_3 ;
    rdf:predicate belv:increases ;
    rdf:subject sub:_1 ;
    a rdf:Statement .
  sub:assertion rdfs:label "cat(p(HGNC:MYD88)) -> kin(p(HGNC:IRAK1))" .
}
sub:provenance {
  beldoc: dce:description "Approximately 61,000 statements." ;
    dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ;
    dce:title "BEL Framework Large Corpus Document" ;
    pav:authoredBy sub:_7 ;
    pav:version "20131211" .
  sub:_6 prov:value "Schematic representation of NE-induced IL-8 signal transduction pathway in human bronchial epithelial cells. In bronchial epithelial cells, NE activates an as yet unidentified receptor. The cytosolic protein MyD88 acts as an adaptor coupling the receptor complex to IRAK. The signal is relayed downstream via TRAF-6 to the I?B kinases (IKKs) (via NIK/MEKK1), resulting in phosphorylation and degradation of I?B?, and subsequent release and translocation of NF?B to the nucleus where it transactivates IL-8 gene expression." ;
    prov:wasQuotedFrom pubmed:11461907 .
  sub:_7 rdfs:label "Selventa" .
  sub:assertion prov:hadPrimarySource pubmed:11461907 ;
    prov:wasDerivedFrom beldoc: , sub:_6 .
}
sub:pubinfo {
  this: dct:created "2014-07-03T14:31:42.732+02:00"^^xsd:dateTime ;
    pav:createdBy orcid:0000-0001-6818-334X , orcid:0000-0002-1267-0234 .
}