[ { "@graph" : [ { "@id" : "http://bio2rdf.org/drugbank:DB00728", "@type" : [ "http://bio2rdf.org/drugbank_vocabulary:Drug" ], "http://bio2rdf.org/bio2rdf_vocabulary:identifier" : [ { "@value" : "DB00728" } ], "http://bio2rdf.org/bio2rdf_vocabulary:namespace" : [ { "@value" : "drugbank" } ], "http://bio2rdf.org/bio2rdf_vocabulary:uri" : [ { "@value" : "http://bio2rdf.org/drugbank:DB00728" } ], "http://bio2rdf.org/bio2rdf_vocabulary:x-identifiers.org" : [ { "@id" : "http://identifiers.org/drugbank/DB00728" } ], "http://bio2rdf.org/drugbank_vocabulary:drugbank-id" : [ { "@value" : "APRD01221" }, { "@value" : "DB00728" } ], "http://bio2rdf.org/drugbank_vocabulary:x-ahfs" : [ { "@id" : "http://bio2rdf.org/ahfs:12:20.00" } ], "http://bio2rdf.org/drugbank_vocabulary:x-atc" : [ { "@id" : "http://bio2rdf.org/atc:M03AC09" } ], "http://bio2rdf.org/drugbank_vocabulary:x-cas" : [ { "@id" : "http://bio2rdf.org/cas:143558-00-3" } ], "http://bio2rdf.org/drugbank_vocabulary:x-chebi" : [ { "@id" : "http://bio2rdf.org/chebi:8884" } ], "http://bio2rdf.org/drugbank_vocabulary:x-chemspider" : [ { "@id" : "http://bio2rdf.org/chemspider:390053" } ], "http://bio2rdf.org/drugbank_vocabulary:x-dpd" : [ { "@id" : "http://bio2rdf.org/dpd:2108208" } ], "http://bio2rdf.org/drugbank_vocabulary:x-gtp" : [ { "@id" : "http://bio2rdf.org/gtp:4003" } ], "http://bio2rdf.org/drugbank_vocabulary:x-iuphar" : [ { "@id" : "http://bio2rdf.org/iuphar:4003" } ], "http://bio2rdf.org/drugbank_vocabulary:x-kegg" : [ { "@id" : "http://bio2rdf.org/kegg:D00765" } ], "http://bio2rdf.org/drugbank_vocabulary:x-ndc" : [ { "@id" : "http://bio2rdf.org/ndc:0781-3220-75" } ], "http://bio2rdf.org/drugbank_vocabulary:x-pharmgkb" : [ { "@id" : "http://bio2rdf.org/pharmgkb:PA164754992" } ], "http://bio2rdf.org/drugbank_vocabulary:x-pubchemcompound" : [ { "@id" : "http://bio2rdf.org/pubchem.compound:441290" } ], "http://bio2rdf.org/drugbank_vocabulary:x-pubchemsubstance" : [ { "@id" : "http://bio2rdf.org/pubchem.substance:46506855" } ], "http://bio2rdf.org/drugbank_vocabulary:x-wikipedia" : [ { "@id" : "http://bio2rdf.org/wikipedia:Rocuronium" } ], "http://purl.org/dc/terms/description" : [ { "@language" : "en", "@value" : "Rocuronium (rapid onset-curonium) is a desacetoxy analogue of vecuronium with a more rapid onset of action. It is an aminosteroid non-depolarizing neuromuscular blocker or muscle relaxant used in modern anaesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.\nIntroduced in 1994, rocuronium has rapid onset, and intermediate duration of action. It is marketed under the trade name of Zemuron in the United States and Esmeron in most other countries.\nThere is considered to be a risk of allergic reaction to the drug in some patients (particularly those with asthma), but a similar incidence of allergic reactions has been observed by using other members of the same drug class (non-depolarizing neuromuscular blocking drugs). The γ-cyclodextrin derivative sugammadex (trade name Bridion) has been recently introduced as a novel agent to reverse the action of rocuronium." } ], "http://purl.org/dc/terms/identifier" : [ { "@value" : "drugbank:DB00728" } ], "http://purl.org/dc/terms/title" : [ { "@language" : "en", "@value" : "Rocuronium" } ], "http://www.w3.org/2000/01/rdf-schema#label" : [ { "@language" : "en", "@value" : "Rocuronium [drugbank:DB00728]" } ], "http://www.w3.org/2000/01/rdf-schema#seeAlso" : [ { "@id" : "http://www.drugbank.ca/drugs/DB00728" }, { "@id" : "http://www.drugs.com/cdi/rocuronium.html" }, { "@id" : "http://www.rxlist.com/cgi/generic2/rocuronium.htm" } ] } ], "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA#assertion" }, { "@graph" : [ { "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA", "@type" : [ "http://www.nanopub.org/nschema#Nanopublication" ], "http://www.nanopub.org/nschema#hasAssertion" : [ { "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA#assertion" } ], "http://www.nanopub.org/nschema#hasProvenance" : [ { "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA#provenance" } ], "http://www.nanopub.org/nschema#hasPublicationInfo" : [ { "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA#publicationInfo" } ] } ], "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA#head" }, { "@graph" : [ { "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA#assertion", "http://www.w3.org/ns/prov#wasDerivedFrom" : [ { "@id" : "http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz" } ] }, { "@id" : "http://bio2rdf.org/drugbank_resource:bio2rdf.dataset.drugbank.R3", "http://www.w3.org/ns/dcat#distribution" : [ { "@id" : "http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz" } ] }, { "@id" : "http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz", "http://purl.org/dc/terms/created" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#dateTime", "@value" : "2015-01-09T17:00:50-05:00" } ], "http://www.w3.org/ns/prov#wasDerivedFrom" : [ { "@id" : "http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00" } ] }, { "@id" : "http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip", "http://www.w3.org/ns/prov#wasAttributedTo" : [ { "@id" : "http://drugbank.ca" } ] }, { "@id" : "http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00", "http://purl.org/pav/retrievedOn" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#dateTime", "@value" : "2014-11-12T07:57:03-05:00" } ], "http://www.w3.org/ns/prov#wasDerivedFrom" : [ { "@id" : "http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip" } ] } ], "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA#provenance" }, { "@graph" : [ { "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA", "http://purl.org/dc/terms/created" : [ { "@type" : "http://www.w3.org/2001/XMLSchema#dateTime", "@value" : "2018-03-30T11:10:51.011+02:00" } ], "http://purl.org/dc/terms/license" : [ { "@id" : "https://creativecommons.org/licenses/by-nc/4.0/" } ], "http://purl.org/nanopub/x/hasSignatureElement" : [ { "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA#signature.MCwCFFlNfxO2OGiZ" } ], "http://www.w3.org/ns/prov#wasGeneratedBy" : [ { "@id" : "https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475" } ] }, { "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA#signature.MCwCFFlNfxO2OGiZ", "http://purl.org/nanopub/x/hasPublicKey" : [ { "@value" : "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" } ], "http://purl.org/nanopub/x/hasSignature" : [ { "@value" : "MCwCFFlNfxO2OGiZxFuRsYhLLC8iT1ffAhQnvoGhHCcV19kONLSPJrSIoG5wnQ==" } ], "http://purl.org/nanopub/x/signedBy" : [ { "@id" : "https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB" } ] }, { "@id" : "https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB", "http://www.w3.org/ns/prov#specializationOf" : [ { "@id" : "https://github.com/tkuhn/bio2rdf2nanopub" } ], "http://www.w3.org/ns/prov#wasAttributedTo" : [ { "@id" : "http://orcid.org/0000-0002-1267-0234" } ] }, { "@id" : "https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475", "http://purl.org/dc/terms/identifier" : [ { "@value" : "7720f136-841b-4851-a6e4-ad20a409a475" } ], "http://www.w3.org/ns/prov#used" : [ { "@id" : "https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349" } ], "http://www.w3.org/ns/prov#wasAssociatedWith" : [ { "@id" : "https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB" } ], "http://www.w3.org/ns/prov#wasStartedBy" : [ { "@id" : "http://orcid.org/0000-0002-1267-0234" } ] }, { "@id" : "https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349", "http://purl.org/dc/terms/isVersionOf" : [ { "@id" : "https://github.com/tkuhn/bio2rdf2nanopub" } ], "http://purl.org/pav/version" : [ { "@value" : "eda7951a5f6c622c5d2132f50c3093138484a349" } ], "http://www.w3.org/ns/prov#wasAttributedTo" : [ { "@id" : "http://orcid.org/0000-0002-1267-0234" } ] } ], "@id" : "http://bio2rdf.org/drugbank:DB00728_nanopub.RAi25scELu7x0En3uciEpjs2JZDhiWPBUTB8cTil7kqZA#publicationInfo" } ]