@prefix this: <http://rdf.disgenet.org/resource/nanopub/NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/resource/nanopub/> .
@prefix dgn-gda: <http://rdf.disgenet.org/resource/gda/> .
@prefix dgn-void: <http://rdf.disgenet.org/v4.0.0/void/> .

dgn-np:NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY130_head {
  this: np:hasAssertion dgn-np:NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY130_assertion;
    np:hasProvenance dgn-np:NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY130_provenance;
    np:hasPublicationInfo dgn-np:NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY130_assertion a np:Assertion .
  
  dgn-np:NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY130_provenance a np:Provenance .
  
  dgn-np:NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY130_assertion {
  miriam-gene:27122 a ncit:C16612 .
  
  lld:C2239176 a ncit:C7057 .
  
  dgn-gda:DGN09801db99f445c4149797145d0020439 sio:SIO_000628 miriam-gene:27122, lld:C2239176;
    a sio:SIO_001121 .
}

dgn-np:NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY130_provenance {
  dgn-np:NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY130_assertion dcterms:description
      "[We found that the sFRP1 gene encoding the subunit is a frequent target of aberrant DNA hypermethylation and silencing in HCC tumours, whereas other extracellular Wnt antagonists, WIF1 and Dkk3, exhibited no methylation in tumour cells, consistent with the notion that aberrant methylation events in cancer cells are non-randomly distributed among the genes and that there is a strong preference for hypermethylation of specific genes in HCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:22351518;
    prov:wasDerivedFrom dgn-void:befree-2016;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-2016 pav:importedOn "2016-02-19"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP962233.RAhdY38SZymyFIjBQBACOxoyvku9cOPHfUx6atXO0d6MY130_publicationInfo {
  this: dcterms:created "2016-05-13T12:49:01+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetv3.0rdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v4.0.0.0" .
  
  dgn-void:disgenetv3.0rdf pav:version "v4.0.0" .
}