@prefix this: <http://rdf.disgenet.org/nanopublications.trig#NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix sio: <http://semanticscience.org/resource/> .
@prefix ncit: <http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#> .
@prefix lld: <http://linkedlifedata.com/resource/umls/id/> .
@prefix miriam-gene: <http://identifiers.org/ncbigene/> .
@prefix miriam-pubmed: <http://identifiers.org/pubmed/> .
@prefix eco: <http://purl.obolibrary.org/obo/eco.owl#> .
@prefix wi: <http://purl.org/ontology/wi/core#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix pav: <http://purl.org/pav/2.0/> .
@prefix prv: <http://purl.org/net/provenance/ns#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix dgn-np: <http://rdf.disgenet.org/nanopublications.trig#> .
@prefix dgn-gda: <http://rdf.disgenet.org/gene-disease-association.ttl#> .
@prefix dgn-void: <http://rdf.disgenet.org/v2.1.0/void.ttl#> .

dgn-np:NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0130_head {
  this: np:hasAssertion dgn-np:NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0130_assertion;
    np:hasProvenance dgn-np:NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0130_provenance;
    np:hasPublicationInfo dgn-np:NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0130_publicationInfo;
    a np:Nanopublication .
  
  dgn-np:NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0130_assertion a np:Assertion .
  
  dgn-np:NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0130_provenance a np:Provenance .
  
  dgn-np:NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0130_publicationInfo a
      np:PublicationInfo .
}

dgn-np:NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0130_assertion {
  miriam-gene:373156 a ncit:C16612 .
  
  lld:C0008626 a ncit:C7057 .
  
  dgn-gda:DGN423cfa56c0721eb5243b3cc9526bf28b sio:SIO_000628 miriam-gene:373156, lld:C0008626;
    a sio:SIO_001121 .
}

dgn-np:NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0130_provenance {
  dgn-np:NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0130_assertion dcterms:description
      "[The initial study found that urine concentrations of the metabolites 1,2-dihydroxy-4-(acetyl) butane (M1) and 1-dihydroxy-2-(N-acetylcysteinyl)-3-butene (M2) and blood concentrations of the hemoglobin adducts N-[2-hydroxy-3-butenyl] valine (HB-Val) and N-[2,3,4-trihydroxy-butyl] valine (THB-Val) constitute excellent biomarkers of exposure, both being highly correlated with BD exposure levels, and that GST genotypes modulate at least one metabolic pathway, but that irreversible genotoxic effects such as chromosome aberrations and HPRT gene mutations are neither associated with BD exposure levels nor with worker genotypes (GST [glutathione-S-transferase]-M1, GSTT1, CYP2E1 (5' promoter), CYP2E1 (intron 6), EH [epoxide hydrolase] 113, EH139, ADH [alcohol dehydrogenase]2 and ADH3).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en;
    wi:evidence dgn-void:source_evidence_literature;
    sio:SIO_000772 miriam-pubmed:16949064;
    prov:wasDerivedFrom dgn-void:befree-20140225;
    prov:wasGeneratedBy eco:ECO_0000203 .
  
  dgn-void:befree-20140225 pav:importedOn "2014-02-25"^^xsd:date .
  
  dgn-void:source_evidence_literature a eco:ECO_0000212;
    rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en;
    rdfs:label "DisGeNET evidence - LITERATURE"@en .
}

dgn-np:NP893335.RAhasCs_nJu_Dhrb_SFNotejMV25ywswEV7FAFnKEY0b0130_publicationInfo {
  this: dcterms:created "2014-10-02T12:41:09+02:00"^^xsd:dateTime;
    dcterms:rights <http://opendatacommons.org/licenses/odbl/1.0/>;
    dcterms:rightsHolder dgn-void:IBIGroup;
    dcterms:subject sio:SIO_000983;
    prv:usedData dgn-void:disgenetrdf;
    pav:authoredBy <http://orcid.org/0000-0001-5999-6269>, <http://orcid.org/0000-0002-7534-7661>,
      <http://orcid.org/0000-0002-9383-528X>, <http://orcid.org/0000-0003-0169-8159>, <http://orcid.org/0000-0003-1244-7654>;
    pav:createdBy <http://orcid.org/0000-0003-0169-8159>;
    pav:version "v2.1.0.0" .
  
  dgn-void:disgenetrdf pav:version "v2.1.0" .
}