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[There is compelling evidence that HIPK2 is also involved in the response to hypoxia by acting as co-suppressor of hypoxia inducible factor 1? (HIF-1?), a major factor in cancer progression that activates the transcription of genes involved in angiogenesis, glucose metabolism and invasion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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