http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#Head
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk
http://www.nanopub.org/nschema#hasAssertion
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#assertion
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk
http://www.nanopub.org/nschema#hasProvenance
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#provenance
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk
http://www.nanopub.org/nschema#hasPublicationInfo
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#pubinfo
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.nanopub.org/nschema#Nanopublication
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#assertion
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_1
http://www.selventa.com/vocabulary/hasSubstitution
S,1798,A
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_1
http://www.selventa.com/vocabulary/variantOf
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=12363
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_1
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_2
http://www.selventa.com/vocabulary/hasSubstitution
G,12,V
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_2
http://www.selventa.com/vocabulary/variantOf
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=5173
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_2
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.ebi.ac.uk/ontology-lookup/?termId=MOD:00000
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_3
http://www.selventa.com/vocabulary/translocationFrom
http://amigo.geneontology.org/amigo/term/GO:0005622
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_3
http://www.selventa.com/vocabulary/translocationOf
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_4
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_3
http://www.selventa.com/vocabulary/translocationTo
http://amigo.geneontology.org/amigo/term/GO:0005576
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_4
http://purl.obolibrary.org/obo/RO_0002204
http://www.genenames.org/cgi-bin/gene_symbol_report?hgnc_id=1504
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_4
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI_36080
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_5
http://www.w3.org/1999/02/22-rdf-syntax-ns#object
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_3
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_5
http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate
http://www.selventa.com/vocabulary/decreases
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_5
http://www.w3.org/1999/02/22-rdf-syntax-ns#subject
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_2
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_5
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_6
http://purl.obolibrary.org/obo/BFO_0000066
http://www.lgcstandards-atcc.org/Products/All/CCL-2.aspx
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_6
http://purl.obolibrary.org/obo/BFO_0000066
http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_6
http://www.w3.org/1999/02/22-rdf-syntax-ns#object
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_5
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_6
http://www.w3.org/1999/02/22-rdf-syntax-ns#predicate
http://www.selventa.com/vocabulary/increases
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_6
http://www.w3.org/1999/02/22-rdf-syntax-ns#subject
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_1
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_6
http://www.w3.org/1999/02/22-rdf-syntax-ns#type
http://www.w3.org/1999/02/22-rdf-syntax-ns#Statement
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#assertion
http://www.w3.org/2000/01/rdf-schema#label
p(HGNC:HRAS,sub(G,12,V)) -| sec(p(HGNC:CASP3))
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#assertion
http://www.w3.org/2000/01/rdf-schema#label
p(HGNC:TSC2,sub(S,1798,A)) -> (p(HGNC:HRAS,sub(G,12,V)) -| sec(p(HGNC:CASP3)))
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#provenance
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
http://purl.org/dc/elements/1.1/description
Approximately 61,000 statements.
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
http://purl.org/dc/elements/1.1/rights
Copyright (c) 2011-2012, Selventa. All rights reserved.
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
http://purl.org/dc/elements/1.1/title
BEL Framework Large Corpus Document
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
http://purl.org/pav/authoredBy
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_8
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
http://purl.org/pav/version
1.4
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_7
http://www.w3.org/ns/prov#value
TSC2 S1798A mutant.Thi s mutant was used to prove that RSK-dependent phosphorylation of tuberin on Ser1798 inhibits its potential to turn off Rheb and to downregulate the activities of mTOR and p70S6K.Mu tation of Ser1798 inhibited most of tuberin phosphorylation and inactivation by RSK (Roux et al., 2004).Invest igating PARP cleavage, caspase 3 cleavage, the percentage of HOPI-positive cells and the percentage of subG1 cells demonstrated that the cell survival effects of activated Ras over tuberin-induced apoptosis are significantly diminished by this mutation in TSC2 (Figures 5a–c).
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_7
http://www.w3.org/ns/prov#wasQuotedFrom
http://www.ncbi.nlm.nih.gov/pubmed/17922028
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_8
http://www.w3.org/2000/01/rdf-schema#label
Selventa
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#assertion
http://www.w3.org/ns/prov#hadPrimarySource
http://www.ncbi.nlm.nih.gov/pubmed/17922028
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#assertion
http://www.w3.org/ns/prov#wasDerivedFrom
http://resource.belframework.org/belframework/1.0/knowledge/large_corpus.bel
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#assertion
http://www.w3.org/ns/prov#wasDerivedFrom
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#_7
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk#pubinfo
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk
http://purl.org/dc/terms/created
2014-07-03T14:30:51.975+02:00
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk
http://purl.org/pav/createdBy
http://orcid.org/0000-0001-6818-334X
http://www.tkuhn.ch/bel2nanopub/RAhRrT7iTD37FFH0vbCHhZLfN2S9nwdfdhf7kGRtTDggk
http://purl.org/pav/createdBy
http://orcid.org/0000-0002-1267-0234