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a(CHEBI:ceramide) -| tscript(p(HGNC:"NKX2-1"))
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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BEL Framework Large Corpus Document
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Ceramide decreases surfactant protein B gene expression via downregulation of TTF-1 DNA binding activity.Electrophoretic mobility shift and reporter assays showed that ceramide reduced the DNA binding activity and transactivation capability of thyroid transcription factor 1 (TTF-1/Nkx2.1), a key factor for SP-B promoter activity.
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Selventa
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2014-07-03T14:32:50.608+02:00
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