@prefix this: <http://bio2rdf.org/drugbank:DB00982_nanopub.RAgyQZ9FmxvMjzsGrg3K6iGc0ezKuhO9Lt1B2CQQSxUpM> .
@prefix sub: <http://bio2rdf.org/drugbank:DB00982_nanopub.RAgyQZ9FmxvMjzsGrg3K6iGc0ezKuhO9Lt1B2CQQSxUpM#> .
@prefix prov: <http://www.w3.org/ns/prov#> .
@prefix dct: <http://purl.org/dc/terms/> .
@prefix pav: <http://purl.org/pav/> .
@prefix orcid: <http://orcid.org/> .
@prefix codebase: <https://github.com/tkuhn/bio2rdf2nanopub> .
@prefix version: <https://github.com/tkuhn/bio2rdf2nanopub/tree/eda7951a5f6c622c5d2132f50c3093138484a349> .
@prefix instance: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB> .
@prefix process: <https://github.com/tkuhn/bio2rdf2nanopub#instance.MIIBtzCCASwGByqGSM44BAEwggEfAoGB.7720f136-841b-4851-a6e4-ad20a409a475> .
@prefix np: <http://www.nanopub.org/nschema#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .
@prefix v: <http://bio2rdf.org/bio2rdf_vocabulary:> .
@prefix d: <http://bio2rdf.org/drugbank:> .
@prefix dv: <http://bio2rdf.org/drugbank_vocabulary:> .
@prefix dr: <http://bio2rdf.org/drugbank_resource:> .
@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix npx: <http://purl.org/nanopub/x/> .

sub:head {
  this: np:hasAssertion sub:assertion;
    np:hasProvenance sub:provenance;
    np:hasPublicationInfo sub:publicationInfo;
    a np:Nanopublication .
}

sub:assertion {
  d:DB00982 v:identifier "DB00982";
    v:namespace "drugbank";
    v:uri "http://bio2rdf.org/drugbank:DB00982";
    v:x-identifiers.org <http://identifiers.org/drugbank/DB00982>;
    dv:drugbank-id "APRD00140", "DB00982";
    dv:x-ahfs <http://bio2rdf.org/ahfs:84:92.00>;
    dv:x-cas <http://bio2rdf.org/cas:4759-48-2>;
    dv:x-chebi <http://bio2rdf.org/chebi:6067>;
    dv:x-dpd <http://bio2rdf.org/dpd:582344>;
    dv:x-kegg <http://bio2rdf.org/kegg:D00348>;
    dv:x-ndc <http://bio2rdf.org/ndc:0004-0155-49>;
    dv:x-pharmgkb <http://bio2rdf.org/pharmgkb:PA450128>;
    dv:x-wikipedia <http://bio2rdf.org/wikipedia:Isotretinoin>;
    dct:description "Isotretinoin is a medication used for the treatment of severe acne. It is sometimes used in prevention of certain skin cancers. It is a retinoid, meaning it derives from vitamin A and is found in small quantities naturally in the body. Isotretinoin binds to and activates nuclear retinoic acid receptors (RAR), thereby regulating cell proliferation and differentiation. This agent also exhibits immunomodulatory and anti-inflammatory responses and inhibits ornithine decarboxylase, thereby decreasing polyamine synthesis and keratinization."@en;
    dct:identifier "drugbank:DB00982";
    dct:title "Isotretinoin"@en;
    a dv:Drug;
    rdfs:label "Isotretinoin [drugbank:DB00982]"@en;
    rdfs:seeAlso <http://www.drugbank.ca/drugs/DB00982>, <http://www.drugs.com/cdi/isotretinoin.html>,
      <http://www.rxlist.com/cgi/generic/isotret.htm> .
}

sub:provenance {
  sub:assertion prov:wasDerivedFrom <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
  
  dr:bio2rdf.dataset.drugbank.R3 dcat:distribution <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> .
  
  <http://download.bio2rdf.org/release/3/drugbank/drugbank.nq.gz> dct:created "2015-01-09T17:00:50-05:00"^^xsd:dateTime;
    prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00> .
  
  <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip#retrieved-on:2014-11-12T07:57:03-05:00>
    pav:retrievedOn "2014-11-12T07:57:03-05:00"^^xsd:dateTime;
    prov:wasDerivedFrom <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> .
  
  <http://www.drugbank.ca/system/downloads/current/drugbank.xml.zip> prov:wasAttributedTo
      <http://drugbank.ca> .
}

sub:publicationInfo {
  sub:signature.MCwCFD8RbmOZEkPI npx:hasPublicKey "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";
    npx:hasSignature "MCwCFD8RbmOZEkPIzdjx+7oE8+5nglQBAhRlhg0Mt8d1Qh4L91tDSaC++aBl5g==";
    npx:signedBy instance: .
  
  this: dct:created "2018-03-30T11:11:04.064+02:00"^^xsd:dateTime;
    dct:license <https://creativecommons.org/licenses/by-nc/4.0/>;
    npx:hasSignatureElement sub:signature.MCwCFD8RbmOZEkPI;
    prov:wasGeneratedBy process: .
  
  instance: prov:specializationOf codebase:;
    prov:wasAttributedTo orcid:0000-0002-1267-0234 .
  
  process: dct:identifier "7720f136-841b-4851-a6e4-ad20a409a475";
    prov:used version:;
    prov:wasAssociatedWith instance:;
    prov:wasStartedBy orcid:0000-0002-1267-0234 .
  
  version: dct:isVersionOf codebase:;
    pav:version "eda7951a5f6c622c5d2132f50c3093138484a349";
    prov:wasAttributedTo orcid:0000-0002-1267-0234 .
}