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[To explore the possibility that activating mutations in the TSC gene may be involved in the pathogenesis of primary hypertension, we screened genomic DNA of 68 individuals from hypertensive families of patients with hypercalciuria for variations using single-strand conformation polymorphism and investigated the functional properties using the Xenopus laevis oocyte expression system.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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