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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE#_6 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE#_5 http://www.w3.org/ns/prov#value To confirm that TNFalpha protein synthesized in the brain of the transgenic animal is biologically active, we quantified expression of TRADD protein. Homogenates of brain sampled from TNFalpha-Tg and non-Tg rats were incubated with a primary antibody that recognizes rat TRADD only after it has been activated through binding of TNFalpha to p55/TNFR1, thereby implying biological activity of the cytokine. Regional expression of TRADD protein was uniformly higher in TNFalpha-Tg rat brain than in non-Tg controls by statistically significant margins. http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE#_5 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/18947406 http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE#_6 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/18947406 http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE#_5 http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE#pubinfo http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE http://purl.org/dc/terms/created 2014-07-03T14:33:27.780+02:00 http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAghnJTV53Y-l1i0FNLycZfAvGbrfISd_0TWAvb-i4msE http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234