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kin(p(HGNC:EGFR)) -> kin(p(HGNC:MAPK3))
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Approximately 61,000 statements.
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Copyright (c) 2011-2012, Selventa. All rights reserved.
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Studies to date suggest that, in these cancers, several (if not all) of the critical downstream signaling pathways, including the phosphoinositide 3-kinase (PI3K)/Akt, signal transducers and activators of transcription, and extracellular signal-regulated kinase 1 and 2 pathways, are solely controlled by EGFR. Thus, when the tumors are exposed to EGFR inhibitors, these intracellular pathways are turned off and the cancer cells undergo apoptosis (21, 22, 24, 25).
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Selventa
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2014-07-03T14:33:21.346+02:00
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