@prefix dcterms: .
@prefix this: .
@prefix sub: .
@prefix beldoc: .
@prefix rdfs: .
@prefix rdf: .
@prefix xsd: .
@prefix dce: .
@prefix pav: .
@prefix np: .
@prefix belv: .
@prefix prov: .
@prefix mgi: .
@prefix proteinModification: .
@prefix psimod: .
@prefix go: .
@prefix scomp: .
@prefix ProteinComplex: .
@prefix hasAgent: .
@prefix species: .
@prefix occursIn: .
@prefix pubmed: .
@prefix orcid: .
sub:Head {
this: np:hasAssertion sub:assertion;
np:hasProvenance sub:provenance;
np:hasPublicationInfo sub:pubinfo;
a np:Nanopublication .
}
sub:assertion {
scomp:AP-1%20Complex a ProteinComplex: .
sub:_1 belv:variantOf mgi:102858;
a proteinModification:, psimod:00696 .
sub:_2 hasAgent: scomp:AP-1%20Complex;
a go:0042789 .
sub:_3 occursIn: species:10090;
rdf:object sub:_2;
rdf:predicate belv:directlyIncreases;
rdf:subject sub:_1;
a rdf:Statement .
sub:assertion rdfs:label "p(MGI:Fosl2,pmod(P,T)) => tscript(complex(SCOMP:\"AP-1 Complex\"))" .
}
sub:provenance {
beldoc: dce:description "Approximately 61,000 statements.";
dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved.";
dce:title "BEL Framework Large Corpus Document";
pav:authoredBy sub:_5;
pav:version "20131211" .
sub:_4 prov:value "Ariadne: Thus, the major components of the AP-1 in MEK-DD-transformed CEFs were shown to be Fra-2 and c-Jun, and Fra-2 was highly phosphorylated, as reported in CEFs transformed by v- src , Ha- ras , and activated raf (17 , 22) . [Regulation] Here, we report that the transcriptional activity of Fra-2/c-Jun heterodimer was greatly enhanced by cotransfecting a constitutively active mutant of MEK1 gene (MEK-DD) into F9 cells, indicating that Fra-2 was converted into an active transactivator after phosphorylation by MAPK.";
prov:wasQuotedFrom pubmed:10359014 .
sub:_5 rdfs:label "Selventa" .
sub:assertion prov:hadPrimarySource pubmed:10359014;
prov:wasDerivedFrom beldoc:, sub:_4 .
}
sub:pubinfo {
this: dcterms:created "2014-07-03T14:31:30.639+02:00"^^xsd:dateTime;
pav:createdBy orcid:0000-0001-6818-334X, orcid:0000-0002-1267-0234 .
}