@prefix this: . @prefix rdfs: . @prefix xsd: . @prefix sio: . @prefix ncit: . @prefix lld: . @prefix miriam-gene: . @prefix miriam-pubmed: . @prefix eco: . @prefix wi: . @prefix prov: . @prefix pav: . @prefix prv: . @prefix dcterms: . @prefix np: . @prefix dgn-np: . @prefix dgn-gda: . @prefix dgn-void: . dgn-np:NP635289.RAg3Z5ytzG7X1Izk6UgDzmQ9Nm2rcPXsgdkPeyxWyw9qw130_head { this: np:hasAssertion dgn-np:NP635289.RAg3Z5ytzG7X1Izk6UgDzmQ9Nm2rcPXsgdkPeyxWyw9qw130_assertion; np:hasProvenance dgn-np:NP635289.RAg3Z5ytzG7X1Izk6UgDzmQ9Nm2rcPXsgdkPeyxWyw9qw130_provenance; np:hasPublicationInfo dgn-np:NP635289.RAg3Z5ytzG7X1Izk6UgDzmQ9Nm2rcPXsgdkPeyxWyw9qw130_publicationInfo; a np:Nanopublication . dgn-np:NP635289.RAg3Z5ytzG7X1Izk6UgDzmQ9Nm2rcPXsgdkPeyxWyw9qw130_assertion a np:Assertion . dgn-np:NP635289.RAg3Z5ytzG7X1Izk6UgDzmQ9Nm2rcPXsgdkPeyxWyw9qw130_provenance a np:Provenance . dgn-np:NP635289.RAg3Z5ytzG7X1Izk6UgDzmQ9Nm2rcPXsgdkPeyxWyw9qw130_publicationInfo a np:PublicationInfo . } dgn-np:NP635289.RAg3Z5ytzG7X1Izk6UgDzmQ9Nm2rcPXsgdkPeyxWyw9qw130_assertion { miriam-gene:5445 a ncit:C16612 . lld:C3825627 a ncit:C7057 . dgn-gda:DGNb60d946d30890d0e01f1c5fdbdd5d375 sio:SIO_000628 miriam-gene:5445, lld:C3825627; a sio:SIO_001123 . } dgn-np:NP635289.RAg3Z5ytzG7X1Izk6UgDzmQ9Nm2rcPXsgdkPeyxWyw9qw130_provenance { dgn-np:NP635289.RAg3Z5ytzG7X1Izk6UgDzmQ9Nm2rcPXsgdkPeyxWyw9qw130_assertion dcterms:description "[As a consequence of PON2 inactivation in the epithelial cells, we observed 1) imbalanced primary and secondary antioxidative responses, characterized by increased superoxide dismutases and decreased catalase, 2) high concentrations of H(2)O(2) and malondialdehyde, along with low glutathione-to-glutathione disulfide ratio, 3) upregulation of TNF-α, IL-6, and monocyte chemoattractant protein-1 gene expression after induction of oxidative stress, and 4) raised level of the activation of transcription factor NF-κB, which was likely implicated in exacerbation of the inflammatory activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en; wi:evidence dgn-void:source_evidence_literature; sio:SIO_000772 miriam-pubmed:22744335; prov:wasDerivedFrom dgn-void:befree-20150227; prov:wasGeneratedBy eco:ECO_0000203 . dgn-void:befree-20150227 pav:importedOn "2015-02-27"^^xsd:date . dgn-void:source_evidence_literature a eco:ECO_0000212; rdfs:comment "Gene-disease associations inferred from text-mining the literature."@en; rdfs:label "DisGeNET evidence - LITERATURE"@en . } dgn-np:NP635289.RAg3Z5ytzG7X1Izk6UgDzmQ9Nm2rcPXsgdkPeyxWyw9qw130_publicationInfo { this: dcterms:created "2015-08-25T14:44:00+02:00"^^xsd:dateTime; dcterms:rights ; dcterms:rightsHolder dgn-void:IBIGroup; dcterms:subject sio:SIO_000983; prv:usedData dgn-void:disgenetv3.0rdf; pav:authoredBy , , , , ; pav:createdBy ; pav:version "v3.0.0.0" . dgn-void:disgenetv3.0rdf pav:version "v3.0.0" . }