sub:provenance { beldoc:dce:description "Approximately 61,000 statements." ; dce:rights "Copyright (c) 2011-2012, Selventa. All rights reserved." ; dce:title "BEL Framework Large Corpus Document" ; pav:authoredBysub:_6 ; pav:version "20131211" . sub:_4dce:identifier "OMIM text for PLAU" ; dce:title "OMIM text for PLAU" ; dce:type "Online Resource" . sub:_5prov:value "In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPA receptor (UPAR, or PLAUR; 173391) signaling complex containing TYK2 (176941) and phosphatidylinositol 3-kinase (PI3K; see 601232). Kiian et al. (2003) showed that association of TYK2 and PI3K with active GTP-bound forms of both RHOA (ARHA; 165390) and RAC1 (602048), but not CDC42 (116952), as well as phosphorylation of myosin light chain (see 160781), are downstream events required for UPA/UPAR-directed migration." ; prov:wasQuotedFromsub:_4 . sub:_6rdfs:label "Selventa" . sub:assertionprov:hadPrimarySourcesub:_4 ; prov:wasDerivedFrombeldoc: , sub:_5 . }