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All rights reserved. http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/dc/elements/1.1/title BEL Framework Large Corpus Document http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/authoredBy http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY#_7 http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://purl.org/pav/version 20131211 http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY#_6 http://www.w3.org/ns/prov#value we examined the requirement for PKCs in the PMA-induced activation of ERKs by using different PKC inhibitors. Treatment with GF109203X resulted in a total inhibition of ERKs activation, whereas rottlerin had no effect (Figure 8). Because rottlerin is unable to block the activation of ERKs by PMA, PKC-d is not implicated in this process. Given that atypical PKCs were not activated by PMA on the XG-6 cells, these results suggest that PKC-z was not involved...Finally, because XG-6 cells express PKC-nu and PKC-d as novel PKC isoforms, we can assume that the novel PKC, namely PCK-nu, is involved in the activation of ERKs by PMA. http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY#_6 http://www.w3.org/ns/prov#wasQuotedFrom http://www.ncbi.nlm.nih.gov/pubmed/11485567 http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY#_7 http://www.w3.org/2000/01/rdf-schema#label Selventa http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY#assertion http://www.w3.org/ns/prov#hadPrimarySource http://www.ncbi.nlm.nih.gov/pubmed/11485567 http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://resource.belframework.org/belframework/20131211/knowledge/large_corpus.bel http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY#_6 http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY#pubinfo http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY http://purl.org/dc/terms/created 2014-07-03T14:31:42.992+02:00 http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY http://purl.org/pav/createdBy http://orcid.org/0000-0001-6818-334X http://www.tkuhn.ch/bel2nanopub/RAferD3B75gO3bMagNeJ4E6oQu4Alb5QwS8TOz0x7urfY http://purl.org/pav/createdBy http://orcid.org/0000-0002-1267-0234